Andriulli A, Pera A, Gindro T, Astegiano M, Verme G
Divisione di Gastroenterologia, Ospedale S. Giovanni Battista-Molinette, Torino.
Minerva Med. 1990 Jan-Feb;81(1-2):55-60.
The diagnosis of intestinal ischaemia still presents numerous problems in terms of nosography, epidemiology, diagnosis and treatment with the result that it is more often excluded than diagnosed. The aim of the present study was to discover whether intestinal ischaemia was clinically identifiable by any specific early signs and symptoms and whether there were any concomitant risk factors. The medical reports on 44 patients consecutively admitted to the San Giovanni Battista Hospital, Turin in 1985-86 with suspected intestinal ischaemia were therefore examined. It was found that intestinal ischaemia was only occasionally (30% of cases) diagnosed at the onset of clinical symptoms. In the 10 patients with ischaemic colitis, the risk factor linked to the causes of the disease was systemic hypovolaemia arising in diffuse atherosclerosis. In the 8 cases of chronic ischaemia and the 26 of intestinal infarction the remote anamnesis revealed symptoms that should have aroused suspicion of intestinal ischaemia partly because the patients were suffering from widespread atherosclerosis. In fact a review of the risk factors for the onset of atherosclerosis (i.e. high blood pressure, smoking, dyslipidemia, obesity and age over 65) revealed that about 60% of the patients under study presented 3 or 4 them simultaneously. To conclude, the data emerging from the study indicate the existence of symptoms and risk factors to diffuse atherosclerosis that should permit the early diagnosis of intestinal ischaemia.
在疾病分类学、流行病学、诊断和治疗方面,肠缺血的诊断仍然存在诸多问题,其结果是肠缺血更多时候是被排除而非被诊断。本研究的目的是探究肠缺血在临床上是否可通过任何特定的早期体征和症状来识别,以及是否存在任何伴随的风险因素。因此,我们检查了1985 - 1986年期间连续入住都灵圣乔瓦尼·巴蒂斯塔医院且疑似肠缺血的44例患者的病历报告。结果发现,肠缺血仅在临床症状出现时偶尔被诊断(30%的病例)。在10例缺血性结肠炎患者中,与疾病病因相关的风险因素是弥漫性动脉粥样硬化引起的全身性血容量不足。在8例慢性缺血和26例肠梗死病例中,既往病史显示出一些本应引起对肠缺血怀疑的症状,部分原因是患者患有广泛的动脉粥样硬化。事实上,对动脉粥样硬化发病风险因素(即高血压、吸烟、血脂异常、肥胖和65岁以上年龄)的回顾显示,约60%的研究对象同时存在3种或4种风险因素。总之,该研究得出的数据表明存在一些症状和弥漫性动脉粥样硬化的风险因素,这应有助于肠缺血的早期诊断。