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外翻畸形中不对称骨骺抑制后的矫正率:使用线性混合模型应用的分析

Rate of correction after asymmetrical physeal suppression in valgus deformity: analysis using a linear mixed model application.

作者信息

Sung Ki Hyuk, Ahn Soyeon, Chung Chin Youb, Lee Kyoung Min, Kim Tae Won, Han Ho Sung, Kim Dae Ha, Choi In Ho, Cho Tae-Joon, Yoo Won Joon, Park Moon Seok

机构信息

Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Kyungki, Korea.

出版信息

J Pediatr Orthop. 2012 Dec;32(8):805-14. doi: 10.1097/BPO.0b013e318273e411.

Abstract

BACKGROUND

This study was performed to estimate the rate of angular correction after asymmetrical physeal suppression and analyze the factors that influence the rate of correction by using a linear mixed model application.

METHODS

A total of 175 physes (72 distal femoral, 70 proximal tibial, and 33 distal tibial) from 78 consecutive patients with valgus angular deformity of the lower limb who underwent asymmetrical physeal suppression were included. The anatomic lateral distal femoral angle, the anatomic lateral proximal tibial angle, and the anatomic lateral distal tibial angle were measured from the teleroentgenograms of the patients' preoperative visit and periodic follow-ups. The rate of angular correction was adjusted by multiple factors by using a linear mixed model with age, sex, and surgical method as the fixed effects and each subject as the random effect. The final model included the age-specific and surgical method-specific rate and sex-specific and surgical method-specific intercept. Multivariate analysis was performed for this model.

RESULTS

In younger children (boys 14 y or younger and girls 12 y or younger), the rate of correction of valgus deformity at the distal femur, proximal tibia, and distal tibia was 0.71 degrees/month (8.5 degrees/y), 0.40 degrees/month (4.8 degrees/y), and 0.48 degrees/month (5.8 degrees/y), respectively. In older children, the rate of correction of valgus deformity at the distal femur, proximal tibia, and distal tibia was 0.39 degrees/month (4.7 degrees/y), 0.29 degrees/month (3.5 degrees/y), and 0.48 degrees/month (5.8 degrees/y), respectively. The rate of correction at the distal femur was significantly lower in older children (P = 0.025). The rate of angular correction at the proximal tibia was significantly faster in the screw group than in the staple group (P = 0.046).

CONCLUSIONS

Asymmetrical physeal suppression with staples, percutaneous transphyseal screws, and permanent method all are effective methods for treating valgus deformity in growing children. When we treat valgus deformity in growing children, we should take into consideration the fact that the rate of correction at the distal femur is lower in older children, and that at the proximal tibia is faster in the screw group.

LEVEL OF EVIDENCE

Therapeutic level III.

摘要

背景

本研究旨在评估不对称骨骺抑制术后的角度矫正率,并通过应用线性混合模型分析影响矫正率的因素。

方法

纳入78例接受不对称骨骺抑制术的下肢外翻角畸形连续患者的175个骨骺(72个股骨远端、70个胫骨近端和33个胫骨远端)。从患者术前及定期随访的远距离X线片测量解剖学外侧股骨远端角、解剖学外侧胫骨近端角和解剖学外侧胫骨远端角。采用以年龄、性别和手术方式为固定效应、每个受试者为随机效应的线性混合模型,对角度矫正率进行多因素校正。最终模型包括年龄特异性和手术方式特异性矫正率以及性别特异性和手术方式特异性截距。对该模型进行多变量分析。

结果

在年幼儿童(14岁及以下男孩和12岁及以下女孩)中,股骨远端、胫骨近端和胫骨远端外翻畸形的矫正率分别为0.71°/月(8.5°/年)、0.40°/月(4.8°/年)和0.48°/月(5.8°/年)。在年长儿童中,股骨远端、胫骨近端和胫骨远端外翻畸形的矫正率分别为0.39°/月(4.7°/年)、0.29°/月(3.5°/年)和0.48°/月(5.8°/年)。年长儿童股骨远端的矫正率显著较低(P = 0.025)。胫骨近端的角度矫正率在螺钉组显著快于钉组(P = 0.046)。

结论

使用钉、经皮穿骨骺螺钉和永久性方法进行不对称骨骺抑制均是治疗生长中儿童外翻畸形的有效方法。在治疗生长中儿童的外翻畸形时,我们应考虑到年长儿童股骨远端的矫正率较低,以及胫骨近端在螺钉组的矫正率较快这一事实。

证据水平

治疗性III级。

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