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一种用于治疗股骨近端骨肉瘤伴关节内扩展的人工关节置换新技术。

A new technique of endoprosthetic replacement for osteosarcoma of proximal femur with intra-articular extension.

作者信息

Oragui E, Nannaparaju M, Sri-Ram K, Khan W, Hashemi-Nejad A, Skinner J

机构信息

Royal National Orthopedic Hospital, Stanmore HA7 4LP, UK.

出版信息

Int J Surg Case Rep. 2013;4(1):101-4. doi: 10.1016/j.ijscr.2012.07.020. Epub 2012 Oct 13.

Abstract

INTRODUCTION

Osteosarcoma is the most common primary malignant tumour of bone and commonly involved sites are the distal femur, proximal tibia, and humerus. Osteosarcoma of proximal femur usually arises at the metaphysis and articular cartilage acts as a relative barrier to tumour spread, with extension into the hip joint being extremely rare.

PRESENTATION OF CASE

A previously fit and well sixteen-year-old male presented with a 2month history of right hip pain and a limp. Plain radiographs and magnetic resonance imaging (MRI) showed an expansile lesion in the right femoral neck, extending 16cm distally from the proximal femoral articular surface through the intertrochanteric region into the upper right femoral shaft. There was also clear evidence of intra-articular extension into the acetabulum.

DISCUSSION

Endoprosthetic replacement following resection is a good treatment option for proximal femoral tumours due to the low complication rate and achievement of good postoperative function. However, treatment of a proximal femoral lesion with intra-articular involvement by prosthetic reconstruction is challenging. We report a patient who presented with osteosarcoma of the proximal femur extending into the hip joint and describe the technique of en-bloc extra-articular resection of the acetabulum and proximal femur with reconstruction using a custom made prosthesis.

CONCLUSION

We conclude that extra-articular resection and endoprosthetic reconstruction using a coned hemi-pelvic implant with fluted stem and a modular femoral implant is a useful treatment option in the management of a proximal femoral lesion involving the hip-joint. It allows adequate tumour clearance and stable reconstruction for rapid post-operative recovery with early mobilisation.

摘要

引言

骨肉瘤是最常见的原发性骨恶性肿瘤,常见受累部位为股骨远端、胫骨近端和肱骨。股骨近端骨肉瘤通常起源于干骺端,关节软骨对肿瘤扩散起到相对屏障作用,极少延伸至髋关节。

病例介绍

一名既往健康的16岁男性,出现右髋疼痛和跛行2个月。X线平片和磁共振成像(MRI)显示右股骨颈有一膨胀性病变,从股骨近端关节面远端16厘米处经转子间区域延伸至右股骨干上段。也有明确证据表明肿瘤已关节内延伸至髋臼。

讨论

由于并发症发生率低且术后功能良好,切除术后行人工关节置换是股骨近端肿瘤的良好治疗选择。然而,对关节内受累的股骨近端病变进行人工关节重建治疗具有挑战性。我们报告一名股骨近端骨肉瘤延伸至髋关节的患者,并描述了使用定制假体对髋臼和股骨近端进行整块关节外切除及重建的技术。

结论

我们得出结论,使用带槽柄的锥形半骨盆植入物和模块化股骨植入物进行关节外切除及人工关节重建,是治疗累及髋关节的股骨近端病变的一种有效治疗选择。它能实现充分的肿瘤清除和稳定的重建,利于术后快速恢复并早期活动。

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