Department of Radiology & Medical Imaging, Division of Vascular Interventional Radiology, University of Virginia Health System, 1215 Lee St, PO Box 800170, Charlottesville, VA 22908, USA.
Cardiovasc Intervent Radiol. 2013 Aug;36(4):1068-72. doi: 10.1007/s00270-012-0510-1. Epub 2012 Nov 14.
This study describes and evaluated the effectiveness of occluding distal ureters in the clinical setting of urinary vaginal (vesicovaginal or enterovesicovaginal) fistulae utilizing a new technique which combines Amplatzer vascular plugs and N-butyl cyanoacrylate.
This is a retrospective study (January 2007-December 2010) of patients with urinary-vaginal fistulae undergoing distal ureter embolization utilizing an Amplatzer-N-butyl cyanoacrylate-Amplatzer sandwich technique. An 8-12-mm type-I or type-II Amplatzer vascular plug was delivered using the sheath and deployed in the ureter distal to the pelvic brim. Instillation of 0.8-1.5 cc of N-butyl cyanoacrylate into ureter proximal to the Amplatzer plug was performed. This was followed by another set of 8-12-mm type-I or type-II Amplatzer vascular plugs in a technique referred to as the "sandwich technique."
Five ureters in three patients were occluded utilizing the above-described technique during the 4-year study period. Mean maximum size Amplatzer used per ureter was 10.8 mm (range, 8-12). One ureter required three Amplatzer plugs and the rest required two. Two patients (3 ureters) were clinically successful with complete resolution of symptoms in 36-48 h. The third patient (2 ureters) was partly successful and required a second Amplatzer-N-butyl cyanoacrylate sandwich technique embolization. The mean clinical follow-up was 11.3 months (range, 1.7-29.2).
The Amplatzer-N-butyl cyanoacrylate-Amplatzer sandwich technique for occluding the distal ureter is safe and effective with a quick (probably due to the N-butyl cyanoacrylate) and durable (probably due to the Amplatzer plugs) clinical response.
本研究描述并评估了在尿阴道(膀胱阴道或肠膀胱阴道)瘘的临床环境中使用一种新的结合 Amplatzer 血管塞和 N-丁基氰基丙烯酸酯的技术来闭塞远端输尿管的效果。
这是一项回顾性研究(2007 年 1 月至 2010 年 12 月),研究对象为接受远端输尿管栓塞术的尿阴道瘘患者,采用 Amplatzer-N-丁基氰基丙烯酸酯-Amplatzer 三明治技术。使用护套输送 8-12mm 型 I 或 II 型 Amplatzer 血管塞,并将其部署在骨盆边缘以下的输尿管远端。将 0.8-1.5cc 的 N-丁基氰基丙烯酸酯注入靠近 Amplatzer 塞的输尿管近端。随后,在所谓的“三明治技术”中,再放置一组 8-12mm 型 I 或 II 型 Amplatzer 血管塞。
在 4 年的研究期间,使用上述技术闭塞了 3 名患者的 5 个输尿管。每个输尿管使用的最大 Amplatzer 平均尺寸为 10.8mm(范围 8-12)。一个输尿管需要三个 Amplatzer 塞,其余需要两个。2 名患者(3 个输尿管)在 36-48 小时内完全缓解症状,治疗成功。第 3 名患者(2 个输尿管)部分成功,需要再次进行 Amplatzer-N-丁基氰基丙烯酸酯三明治栓塞技术。平均临床随访时间为 11.3 个月(范围 1.7-29.2)。
Amplatzer-N-丁基氰基丙烯酸酯-Amplatzer 三明治技术闭塞远端输尿管是安全有效的,具有快速(可能由于 N-丁基氰基丙烯酸酯)和持久(可能由于 Amplatzer 塞)的临床反应。