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使用Amplatzer血管封堵器II进行经肾输尿管封堵术:一种治疗下尿路瘘的新介入治疗选择。

Transrenal ureteral occlusion using the Amplatzer vascular plug II: a new interventional treatment option for lower urinary tract fistulas.

作者信息

Pieper Claus Christian, Meyer Carsten, Hauser Stefan, Wilhelm Kai E, Schild Hans Heinz

机构信息

Department of Radiology, University of Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany,

出版信息

Cardiovasc Intervent Radiol. 2014 Apr;37(2):451-7. doi: 10.1007/s00270-013-0662-7. Epub 2013 Jun 8.

Abstract

PURPOSE

This study was designed to evaluate the results of a novel technique for transrenal ureteral occlusion using an Amplatzer vascular plug (AVP) II in patients with urinary fistulas.

METHODS

We retrospectively evaluated the results of transrenal occlusion of 15 ureters in 9 hospitalized patients [8 females, 1 male, mean age 64 (range 52-79) years] suffering from pelvic malignancy (4 cervix-carcinomas, 3 bladder-carcinomas, 1 colorectal carcinoma, and 1 vulva-carcinoma). Seven patients were treated for urinary fistulas (4 ureteroenteral, 3 vesicovaginal); the others showed ileum-conduit-insufficiency and Mainz-pouch incontinence, respectively. From 2008 to 2009, an AVP was used in combination with coils and tissue adhesive (n = 5). Since 2009, ureteral occlusions were performed using a latex-covered AVP (n = 10). All patients had previous nephrostomy with only incomplete clinical improvement.

RESULTS

Fourteen of 15 interventions were technically successful. Four of five ureters occluded with a combination of AVP, coils, and tissue adhesive were permanently sealed after a single procedure, whereas one showed slight leakage. After placement of two additional coils 20 days later, permanent occlusion was achieved [mean follow-up 195 (range 30-687) days]. Nine of ten ureters occluded with a latex-covered AVP were completely sealed after a single intervention [mean follow-up 152 (range 10-462) days]. In one case, the latex-cover dislocated during implantation. The AVP alone failed to provide complete dryness. There were no dislocations of the AVP or other major complications.

CONCLUSIONS

Transrenal ureteral occlusion using an AVP is a practical, simple, and quick method and can be advantageous in palliative patients suffering from pelvic malignancy.

摘要

目的

本研究旨在评估使用Amplatzer血管封堵器(AVP)II经肾输尿管封堵术治疗尿瘘患者的新技术效果。

方法

我们回顾性评估了9例住院患者(8例女性,1例男性,平均年龄64岁,范围52 - 79岁)的15条输尿管经肾封堵结果,这些患者患有盆腔恶性肿瘤(4例宫颈癌、3例膀胱癌、1例结直肠癌和1例外阴癌)。7例患者因尿瘘接受治疗(4例输尿管肠瘘、3例膀胱阴道瘘);其他患者分别表现为回肠代膀胱功能不全和迈因茨袋失禁。2008年至2009年,5例患者使用AVP联合弹簧圈和组织粘合剂进行封堵。自2009年起,10例患者使用乳胶覆盖的AVP进行输尿管封堵。所有患者此前均行肾造瘘术,但临床改善不完全。

结果

15次干预中有14次技术成功。5条使用AVP、弹簧圈和组织粘合剂联合封堵的输尿管中,4条在单次手术后永久封堵,1条有轻微渗漏。20天后再放置2个弹簧圈后实现永久封堵[平均随访195天(范围30 - 687天)]。10条使用乳胶覆盖的AVP封堵的输尿管中,9条在单次干预后完全封堵[平均随访152天(范围10 - 462天)]。1例患者在植入过程中乳胶覆盖物移位。仅使用AVP未能实现完全干燥。未发生AVP移位或其他重大并发症。

结论

使用AVP经肾输尿管封堵术是一种实用、简单且快速的方法,对患有盆腔恶性肿瘤的姑息患者可能有益。

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