Pieper Claus Christian, Meyer Carsten, Hauser Stefan, Wilhelm Kai E, Schild Hans Heinz
Department of Radiology, University of Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany,
Cardiovasc Intervent Radiol. 2014 Apr;37(2):451-7. doi: 10.1007/s00270-013-0662-7. Epub 2013 Jun 8.
This study was designed to evaluate the results of a novel technique for transrenal ureteral occlusion using an Amplatzer vascular plug (AVP) II in patients with urinary fistulas.
We retrospectively evaluated the results of transrenal occlusion of 15 ureters in 9 hospitalized patients [8 females, 1 male, mean age 64 (range 52-79) years] suffering from pelvic malignancy (4 cervix-carcinomas, 3 bladder-carcinomas, 1 colorectal carcinoma, and 1 vulva-carcinoma). Seven patients were treated for urinary fistulas (4 ureteroenteral, 3 vesicovaginal); the others showed ileum-conduit-insufficiency and Mainz-pouch incontinence, respectively. From 2008 to 2009, an AVP was used in combination with coils and tissue adhesive (n = 5). Since 2009, ureteral occlusions were performed using a latex-covered AVP (n = 10). All patients had previous nephrostomy with only incomplete clinical improvement.
Fourteen of 15 interventions were technically successful. Four of five ureters occluded with a combination of AVP, coils, and tissue adhesive were permanently sealed after a single procedure, whereas one showed slight leakage. After placement of two additional coils 20 days later, permanent occlusion was achieved [mean follow-up 195 (range 30-687) days]. Nine of ten ureters occluded with a latex-covered AVP were completely sealed after a single intervention [mean follow-up 152 (range 10-462) days]. In one case, the latex-cover dislocated during implantation. The AVP alone failed to provide complete dryness. There were no dislocations of the AVP or other major complications.
Transrenal ureteral occlusion using an AVP is a practical, simple, and quick method and can be advantageous in palliative patients suffering from pelvic malignancy.
本研究旨在评估使用Amplatzer血管封堵器(AVP)II经肾输尿管封堵术治疗尿瘘患者的新技术效果。
我们回顾性评估了9例住院患者(8例女性,1例男性,平均年龄64岁,范围52 - 79岁)的15条输尿管经肾封堵结果,这些患者患有盆腔恶性肿瘤(4例宫颈癌、3例膀胱癌、1例结直肠癌和1例外阴癌)。7例患者因尿瘘接受治疗(4例输尿管肠瘘、3例膀胱阴道瘘);其他患者分别表现为回肠代膀胱功能不全和迈因茨袋失禁。2008年至2009年,5例患者使用AVP联合弹簧圈和组织粘合剂进行封堵。自2009年起,10例患者使用乳胶覆盖的AVP进行输尿管封堵。所有患者此前均行肾造瘘术,但临床改善不完全。
15次干预中有14次技术成功。5条使用AVP、弹簧圈和组织粘合剂联合封堵的输尿管中,4条在单次手术后永久封堵,1条有轻微渗漏。20天后再放置2个弹簧圈后实现永久封堵[平均随访195天(范围30 - 687天)]。10条使用乳胶覆盖的AVP封堵的输尿管中,9条在单次干预后完全封堵[平均随访152天(范围10 - 462天)]。1例患者在植入过程中乳胶覆盖物移位。仅使用AVP未能实现完全干燥。未发生AVP移位或其他重大并发症。
使用AVP经肾输尿管封堵术是一种实用、简单且快速的方法,对患有盆腔恶性肿瘤的姑息患者可能有益。