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听觉幻觉的常见机制-癫痫的灌注研究。

Common mechanisms of auditory hallucinations-perfusion studies in epilepsy.

机构信息

Institute for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, and University of Bern, Switzerland.

出版信息

Psychiatry Res. 2013 Mar 30;211(3):268-70. doi: 10.1016/j.pscychresns.2012.06.007. Epub 2012 Nov 13.

DOI:10.1016/j.pscychresns.2012.06.007
PMID:23154091
Abstract

Auditory hallucinations (AH) occur in various neurological and psychiatric disorders. In psychosis, increased neuronal activity in the primary auditory cortex (PAC) contributes to AH. We investigated functional neuroanatomy of epileptic hallucinations by measuring cerebral perfusion in three patients with AH during simple partial status epilepticus. Hyperperfusion in the temporal lobe covering the PAC occurred in all patients. Our perfusion data support the hypothesis of PAC being a constituting element in the genesis of AH independent of their aetiology.

摘要

听觉幻觉 (AH) 可见于各种神经和精神疾病。在精神病中,初级听觉皮层 (PAC) 的神经元活动增加与 AH 有关。我们通过测量 3 例单纯部分性癫痫持续状态患者的 AH 期间的脑灌注来研究癫痫性幻觉的功能神经解剖。所有患者的颞叶(覆盖 PAC)均出现过度灌注。我们的灌注数据支持 PAC 是 AH 发生的组成元素的假说,而与病因无关。

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