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自杀行为危险因素识别中的统计学问题:生存分析的应用

Statistical issues in the identification of risk factors for suicidal behavior: the application of survival analysis.

作者信息

Leon A C, Friedman R A, Sweeney J A, Brown R P, Mann J J

机构信息

Department of Psychiatry, Cornell University Medical College, New York, NY 10021.

出版信息

Psychiatry Res. 1990 Jan;31(1):99-108. doi: 10.1016/0165-1781(90)90112-i.

Abstract

Studies of suicide risk factors generally examine suicidal behavior as a dichotomous outcome. Survival analytic techniques are discussed in which the time until a suicide attempt from a specific point, such as prior attempt or onset of illness, is also examined. These procedures can incorporate information on those lost to followup or "censored." One survival analytic technique, Cox's proportional hazards model, is a particularly informative statistical technique for the study of suicidal risk factors because several covariates can be incorporated. Illustrative analyses estimate the significance of different risk factors, and demonstrate that there is a 32% increase in the relative risk of a suicide attempt associated with each prior attempt.

摘要

自杀风险因素的研究通常将自杀行为视为一种二分结果。文中讨论了生存分析技术,其中还研究了从特定时间点(如前一次自杀未遂或疾病发作)到自杀未遂的时间。这些程序可以纳入失访或“删失”者的信息。一种生存分析技术,即Cox比例风险模型,是研究自杀风险因素特别有用的统计技术,因为它可以纳入几个协变量。示例分析估计了不同风险因素的显著性,并表明与每次前一次自杀未遂相关的自杀未遂相对风险增加了32%。

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