Babaev R A, Kocharli R Kh, Akhmedova G Sh, Gasanova A A, Babaev Kh F
Radiobiologiia. 1990 Jan-Feb;30(1):57-61.
A study was made of the effect of L-DOPA on the dynamics of changes in lipid peroxidation products (LPP) and the content of various types of SH groups in certain brain structures (oblongata, cerebellum, visual and sensorimotor cortex) and their synaptosomal fractions upon irradiation. The preadministration of L-DOPA to irradiated rats inhibited LPP accumulation, prevented the decrease in the content of various types of thiols and thus exerted an antioxidant effect.
研究了左旋多巴(L-DOPA)对脂质过氧化产物(LPP)动态变化以及辐照后某些脑结构(延髓、小脑、视觉和感觉运动皮层)及其突触体部分中各类SH基团含量的影响。对受辐照大鼠预先给予L-DOPA可抑制LPP积累,防止各类硫醇含量降低,从而发挥抗氧化作用。