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[左旋多巴对辐照期间不同脑结构中脂质过氧化产物积累的影响]

[The effect of L-DOPA on the accumulation of lipid peroxidation products in separate brain structures during irradiation].

作者信息

Babaev R A, Kocharli R Kh, Akhmedova G Sh, Gasanova A A, Babaev Kh F

出版信息

Radiobiologiia. 1990 Jan-Feb;30(1):57-61.

PMID:2315461
Abstract

A study was made of the effect of L-DOPA on the dynamics of changes in lipid peroxidation products (LPP) and the content of various types of SH groups in certain brain structures (oblongata, cerebellum, visual and sensorimotor cortex) and their synaptosomal fractions upon irradiation. The preadministration of L-DOPA to irradiated rats inhibited LPP accumulation, prevented the decrease in the content of various types of thiols and thus exerted an antioxidant effect.

摘要

研究了左旋多巴(L-DOPA)对脂质过氧化产物(LPP)动态变化以及辐照后某些脑结构(延髓、小脑、视觉和感觉运动皮层)及其突触体部分中各类SH基团含量的影响。对受辐照大鼠预先给予L-DOPA可抑制LPP积累,防止各类硫醇含量降低,从而发挥抗氧化作用。

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Radiobiologiia. 1990 Jan-Feb;30(1):57-61.
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