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[胱胺和美沙明的辐射防护作用机制]

[The mechanism of the radioprotective action of cystamine and mexamine].

作者信息

Chigareva N G, Morozova I N, Deev S P

出版信息

Radiobiologiia. 1990 Jan-Feb;30(1):84-7.

PMID:2315463
Abstract

It was found that at the time when cystamine and mexamine exert their maximum radioprotective action DNA synthesis rate decreases in bone marrow cells, the ratio between the colony-forming units in the bone marrow and peripheral blood changes, and functional activity of neutrophils increases.

摘要

结果发现,在胱胺和六甲蜜胺发挥其最大辐射防护作用时,骨髓细胞中的DNA合成速率降低,骨髓和外周血中集落形成单位的比例发生变化,中性粒细胞的功能活性增加。

相似文献

1
[The mechanism of the radioprotective action of cystamine and mexamine].[胱胺和美沙明的辐射防护作用机制]
Radiobiologiia. 1990 Jan-Feb;30(1):84-7.
2
[Cellular mechanism of the radioprotective effect of mexamine on the colony-forming elements of bone marrow].[美克明对骨髓集落形成细胞的辐射防护作用的细胞机制]
Radiobiologiia. 1974 Mar-Apr;14(2):290-2.
3
[Influence of 5-methoxytryptamine, cystamine, and aminopropyl-aminoethylthiophosphate on the radiosensitivity of hematopoietic stem cells].[5-甲氧基色胺、胱胺和氨丙基-氨乙基硫代磷酸酯对造血干细胞放射敏感性的影响]
Radiobiologiia. 1975 Sep-Oct;15(5):766-8.
4
[Radioprotective effect of cystamine and mexamine in 2 sequential cell divisions].
Radiobiologiia. 1981 May-Jun;21(3):368-73.
5
Protective effect of a mixture of radioprotector substances (mexamine and cystamine) on the haematopoietic stem cells of mice.辐射防护物质混合物(美克西明和胱胺)对小鼠造血干细胞的保护作用。
Strahlentherapie. 1975 Sep;150(3):336-43.
6
[Use of monolayer cultures of guinea pig spleen for evaluating the radioprotective effect of mexamine on the survival of colony-forming cells].[利用豚鼠脾脏单层培养物评估美沙明对集落形成细胞存活的辐射防护作用]
Radiobiologiia. 1976 Jan-Feb;16(1):117-20.
7
[Radioprotective effectiveness of a combination of mexamine and cystamine and their combined effect on respiratory exchange in mice].[美克明与胱胺联合应用对小鼠的辐射防护效果及其对呼吸交换的联合作用]
Radiobiologiia. 1976 Jan-Feb;16(1):83-7.
8
[Anti-radiation effectiveness of cystamine and mexamine on mouse hematopoietic stem cells in vivo].
Radiobiologiia. 1977 Mar-Apr;17(2):254-8.
9
Total and local hemodynamic changes in rats following intramuscular administration of a radioprotective mixture of cystamine and mexamine.大鼠肌肉注射半胱胺和美沙明的辐射防护混合物后的全身和局部血流动力学变化。
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove. 1982;25(1):105-12.
10
Increased protective effect of cystamine and mexamine against radiation after activation of the haemopoiesis by dextran sulphate in mice.
Acta Radiol Oncol. 1985 Mar-Apr;24(2):193-8. doi: 10.3109/02841868509134386.

引用本文的文献

1
Comments on the mechanisms of action of radiation protective agents: basis components and their polyvalence.辐射防护剂作用机制述评:基础成分及其多价性
Springerplus. 2014 Aug 7;3:414. doi: 10.1186/2193-1801-3-414. eCollection 2014.