Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Chin Med J (Engl). 2012 Nov;125(22):4142-4.
Antiphospholipid syndrome (APS) refers to a group of clinical symptoms and signs caused by antiphospholipid antibody (aPLA). We reported a rare case of poor outcome of a pregnant woman with APS. The pregnant woman had APS, hemolytic anemia, elevated liver function and low platelet count (HELLP) syndrome, and eclampsia and had a poor outcome from a second pregnancy. She was treated with antispasmodics, sedatives, and anti-hypertensive agents, along with anticoagulant therapy and infusion of immunoglobulin. APS during pregnancy often makes pregnancy even more complex and risky. Obstetricians should carry out anticoagulation treatment throughout the perinatal period.
抗磷脂综合征(APS)是指由抗磷脂抗体(aPLA)引起的一组临床症状和体征。我们报道了一例 APS 孕妇不良结局的罕见病例。该孕妇患有 APS、溶血性贫血、肝功能升高和血小板计数降低(HELLP)综合征以及子痫,第二次妊娠结局不良。她接受了解痉药、镇静剂和抗高血压药物治疗,以及抗凝治疗和免疫球蛋白输注。妊娠期间的 APS 常使妊娠更加复杂和危险。产科医生应在围产期全程进行抗凝治疗。