Neonatal Unit, University of Turin, 10126 Turin, Italy.
J Biol Regul Homeost Agents. 2012 Jul-Sep;26(3 Suppl):25-9.
Hyperbilirubinemia and jaundice are natural, physiological phenomena which are only to be expected in the neonatal period, within certain limits. The highest percentage of jaundice in breastfed newborns should be evaluated in connection with inadequate management of breastfeeding rather than a direct effect of breast milk. Breastfeeding is also linked to visible jaundice persisting beyond the first two weeks of life (breast milk jaundice), but the appearance of skin jaundice is not a reason for interrupting breastfeeding which can and should continue without any interruption in most cases. There have been numerous contributions to the literature which have rescaled the direct role of breast milk both in early jaundice and in the more severe cases of late jaundice. The reviewed guidelines for detection and management of hyperbilirubinemia underline how prevention of badly managed breastfeeding and early support for the couple mother-child are effective prevention measures against severe early-onset jaundice; furthermore, the breastfeeding interruption is no longer recommended as a diagnostic procedure to identify breast milk jaundice because of its low specificity and the risk to disregarding the detection of a potentially dangerous disease.
高胆红素血症和黄疸是自然的、生理现象,仅在一定限度内的新生儿期才会出现。母乳喂养新生儿的黄疸发生率最高,应与母乳喂养管理不当有关,而不是母乳的直接作用。母乳喂养还与出生后两周内持续可见的黄疸(“母乳性黄疸”)有关,但皮肤黄疸的出现并不是中断母乳喂养的理由,在大多数情况下,母乳喂养可以且应该在没有任何中断的情况下继续进行。大量文献对母乳在早期黄疸和更严重的晚期黄疸中的直接作用进行了重新评估。对高胆红素血症检测和管理的审查指南强调了预防管理不当的母乳喂养和对母婴夫妇的早期支持是预防严重早发性黄疸的有效措施;此外,由于其特异性低且有忽略潜在危险疾病检测的风险,母乳喂养中断不再被推荐作为识别母乳性黄疸的诊断程序。