Department of Cardiology and Cardiovascular Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar; Cardiology Section, Al-Khor Hospital, Hamad Medical Corporation, Doha, Qatar.
Int J Cardiol. 2013 Sep 30;168(2):975-80. doi: 10.1016/j.ijcard.2012.10.041. Epub 2012 Nov 15.
Most of the published research on atrial fibrillation (AF) is limited to studies in the developed world and included mainly Caucasian patients. Data about women with AF among other ethnicities is very limited.
The aim of this study was to compare the clinical characteristics, treatment and outcome of women to men hospitalized with AF in a middle-eastern country.
Retrospective analysis of prospective registry of all patients hospitalized with AF in Qatar from 1991 through 2010 was made. Clinical characteristics, management, and outcomes of AF patients were compared according to gender.
During the 20-years period; 1417 women and 2432 men were hospitalized for AF. Women were 5 years older and more likely to have diabetes mellitus, hypertension, and chronic renal impairment and were also less likely to be current smokers and to have ischemic heart disease and impaired left ventricular function when compared to men. There was no gender preference in the use of anticoagulation. The prevalence of concomitant ischemic heart disease and hypertension increased, while the prevalence of valvular heart disease and heart failure decreased among patients hospitalized with AF over the study period. In-hospital mortality and stroke rates were comparable between the two groups.
Women hospitalized with atrial fibrillation were older in age and had higher prevalence of co-morbid cardiovascular risk factors compared to men whereas, mortality and stroke rates were comparable.
大多数已发表的房颤（AF）研究仅限于发达国家的研究，且主要纳入了白种人患者。关于其他族裔女性房颤的数据非常有限。
本研究旨在比较中东国家住院房颤女性与男性患者的临床特征、治疗和结局。
对 1991 年至 2010 年期间在卡塔尔住院的所有房颤患者前瞻性登记的回顾性分析。根据性别比较房颤患者的临床特征、管理和结局。
在 20 年期间，有 1417 名女性和 2432 名男性因 AF 住院。与男性相比，女性年龄大 5 岁，更有可能患有糖尿病、高血压和慢性肾功能不全，且更不可能是当前吸烟者，也更不可能患有缺血性心脏病和左心室功能障碍。在抗凝治疗方面，没有性别偏好。在研究期间，与 AF 住院相关的合并缺血性心脏病和高血压的患病率增加，而瓣膜性心脏病和心力衰竭的患病率下降。两组患者的住院死亡率和卒中发生率相当。
与男性相比，因房颤住院的女性年龄更大，且合并心血管危险因素的患病率更高，而死亡率和卒中发生率相当。
