急性冠状动脉综合征患者的血糖管理。

Management of blood glucose in patients with acute coronary syndromes.

机构信息

Yale University School of Medicine, New Haven, CT, USA.

出版信息

Rev Cardiovasc Med. 2012;13(2-3):e77-88. doi: 10.3909/ricm0615.

Abstract

Hyperglycemia during admission for acute myocardial infarction (MI) is common and associated with poor outcomes. Prior studies employed two distinct approaches to improve outcomes in patients with acute MI--one focused on glucose control, and the other on provision of glucose, insulin, and potassium. However, despite multiple largescale studies, the benefits of glucose lowering in the setting of acute MI remain unclear. This article reviews data from observational studies and clinical trials and synthesizes this information into practical recommendations based on available evidence.

摘要

急性心肌梗死（MI）住院期间的高血糖很常见，且与不良预后相关。既往研究采用两种截然不同的方法来改善急性 MI 患者的结局——一种方法侧重于血糖控制，另一种方法侧重于提供葡萄糖、胰岛素和钾。然而，尽管进行了多项大规模研究，但急性 MI 患者血糖降低的获益仍不明确。本文综述了观察性研究和临床试验的数据，并根据现有证据将这些信息综合为实用建议。