Department of Chemistry, Fudan University, Shanghai, 200433, P.R. China.
Org Biomol Chem. 2013 Jan 14;11(2):248-51. doi: 10.1039/c2ob27044g. Epub 2012 Nov 19.
Pillar[5]arenes with introverted amino groups were produced through aminolysis. X-ray analysis demonstrated that the intramolecular hydrogen bonding induced the amino group toward the inner space of the cavity. The kinetic studies and molecular modelings revealed that the hydrogen bonding also contributed to the acceleration of the aminolysis through stabilizing the intermediate.
通过氨解反应制备了具有内向氨基的 Pillar[5]芳烃。X 射线分析表明，分子内氢键促使氨基朝向空腔内部。动力学研究和分子模拟表明，氢键通过稳定中间产物也有助于加速氨解反应。
