Oral and Maxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
In Vivo. 2012 Nov-Dec;26(6):1045-8.
The differential diagnosis of osseous jaw lesions includes numerous entities. A specific mandibular bone defect known as Stafne's cavity or cyst presents wirh a characteristic cyst-like lesion on radiographs of the jaw. Although the differential diagnosis from other jaw lesions is mandatory, this lesion does not usually require surgical therapy. Current theories concerning the pathogenesis of Stafne's cavity prefer bone depression as a consequence of constant pressure arising from an adjacent salivary gland. We present a case of a large Stafne's cavity eroding the basal mandibular cortex that was found accidentally on an orthopantogram taken for diagnosis of dental diseases. The patient noted a slight pain on pressure during physical investigation. The lesion was completely occupied by fatty tissue, as shown during surgical exploration and as revealed by histological investigation of the specimen. The theory of parenchymal pressure as the cause of mandibular bone depression appears to be inapplicable in the present case. The pathogenesis of Stafne's cavity is still obscure. Differential diagnosis of mandibular lesions is essential in adequate treatment planning.
颌骨病变的鉴别诊断包括许多病症。一种被称为 Stafne 腔或囊肿的特定下颌骨缺损，在颌骨的射线照片上呈现出一种特征性的囊肿样病变。尽管必须与其他颌骨病变进行鉴别诊断，但该病变通常不需要手术治疗。目前关于 Stafne 腔发病机制的理论倾向于将骨凹陷归因于来自相邻唾液腺的持续压力。我们报告了一例大的 Stafne 腔侵蚀下颌骨基底层的病例，该病例是在为诊断牙科疾病拍摄的全口曲面断层片中偶然发现的。患者在体格检查时按压时感到轻微疼痛。在手术探查时可以看到病变完全被脂肪组织占据，并且通过对标本的组织学研究也证实了这一点。实质性压力导致下颌骨凹陷的理论似乎不适用于本病例。Stafne 腔的发病机制仍然不清楚。下颌骨病变的鉴别诊断对于适当的治疗计划至关重要。
