Department of Clinical Medicine and Immunological Sciences, Dermatology Section, University of Siena , Italy.
J Dermatolog Treat. 2014 Apr;25(2):189-92. doi: 10.3109/09546634.2012.751480. Epub 2013 Feb 3.
Fournier's gangrene is a rare polymicrobial necrotising soft tissue infection affecting the perineum and scrotum. It is rapidly progressive, destructive and associated with high morbidity and mortality. Management protocol includes prompt diagnosis, early institution of antibiotic therapy and adequate wound debridement, usually requiring multiple operations. Rapid accurate diagnosis is crucial for successful outcome, while early aggressive surgical intervention together with fluid, hemodynamic and nutritional support and broad-spectrum antibiotics are essential to reduce mortality. Dermatologists are often the first specialist consulted. Two cases of Fournier's gangrene are reported in this report. The aim of the report is to underline the importance of an immediate diagnostic approach to save patients, favoured by a close collaboration among dermatologist, surgeon and urologist.
Fournier 坏疽是一种罕见的多微生物坏死性软组织感染,影响会阴和阴囊。它进展迅速、具有破坏性,并伴有高发病率和死亡率。治疗方案包括及时诊断、早期应用抗生素治疗和充分的清创,通常需要多次手术。快速准确的诊断对于成功治疗至关重要,而早期积极的手术干预、液体、血流动力学和营养支持以及广谱抗生素的使用对于降低死亡率是必不可少的。皮肤科医生通常是首先咨询的专家。本文报告了两例 Fournier 坏疽病例。报告的目的是强调及时诊断方法的重要性,以拯救患者,这得益于皮肤科医生、外科医生和泌尿科医生之间的密切合作。