Department of Ophthalmology, Landspítali - The National University Hospital of Iceland, Reykjavik, IcelandSchool of Medicine, University of Iceland, Reykjavik, IcelandDepartment of Pathology, Landspítali - The National University Hospital of Iceland, Reykjavik, Iceland.
Acta Ophthalmol. 2014 Mar;92(2):121-5. doi: 10.1111/aos.12004. Epub 2012 Nov 20.
To determine the incidence rate as well as causative diagnoses and surgical indications of enucleation in Iceland during the years 1992-2004.
A retrospective population-based incidence study involving the entire population of Iceland. Medical records of all patients who underwent enucleation in Iceland from January 1992 through December 2004 were reviewed. The annually updated Icelandic census was used as a denominator data.
Fifty-six eyes were enucleated during 1992-2004. No eviscerations were done, and the three exenterations performed were not included in the study. The mean annual age-adjusted incidence rate of enucleation in Iceland was 1.48 enucleations per 100 000 population in comparison with 2.66 enucleations per 100 000 for the time period 1964-1991. With advancing age, a significant increasing linear trend existed (p < 0.001). The median age at enucleation was 51 years (SD 22; mean 55 years; 16-91 years). The three most common surgical indications for enucleation were blind painful eye, suspected ocular malignancy and acute trauma. The most common causative diagnosis for enucleation was traumatic lesion (39%). The annual incidence was 2.00 enucleations per 100 000 for men and 0.95 for women. There were significantly more men in the traumatic lesion group (p < 0.001), but no gender predominance was found in the other groups of causative diagnoses (p = 0.8).
The overall mean annual incidence of enucleation in Iceland is continually decreasing, although the incidence of severe ocular trauma and ocular malignancy is fairly stable.
确定 1992-2004 年期间冰岛眼球摘除的发生率以及病因诊断和手术适应证。
这是一项基于人群的回顾性发生率研究，涉及冰岛的全部人口。对 1992 年 1 月至 2004 年 12 月期间在冰岛行眼球摘除术的所有患者的病历进行了回顾。使用每年更新的冰岛人口普查数据作为分母数据。
1992-2004 年期间共行 56 例眼球摘除术。未行眼内容剜除术，且其中 3 例次眶内容剜除术未纳入本研究。与 1964-1991 年期间的 2.66 例眼球摘除术/10 万人相比，冰岛眼球摘除术的年龄校正年平均发生率为 1.48 例眼球摘除术/10 万人。随着年龄的增长，呈显著线性递增趋势（p < 0.001）。眼球摘除的中位年龄为 51 岁（标准差 22；平均 55 岁；16-91 岁）。眼球摘除的 3 个最常见手术适应证为：盲且疼痛的眼、可疑眼部恶性肿瘤和急性创伤。眼球摘除的最常见病因诊断为外伤性病变（39%）。每年的眼球摘除发生率为男性 2.00 例眼球摘除术/10 万人，女性 0.95 例眼球摘除术/10 万人。创伤性病变组中男性显著多于女性（p < 0.001），但其他病因诊断组中未发现性别优势（p = 0.8）。
尽管严重眼部创伤和眼部恶性肿瘤的发生率相对稳定，但冰岛眼球摘除的总体平均年发生率持续下降。
