衰老的性腺、腺体和配子：不可改变还是部分可逆的变化？
Aging gonads, glands, and gametes: immutable or partially reversible changes?
机构信息
Reproductive Partners Medical Group, Redondo Beach, California.
出版信息
Fertil Steril. 2013 Jan;99(1):1-4. doi: 10.1016/j.fertnstert.2012.10.044. Epub 2012 Nov 17.
Abstract
Decreased ovarian testosterone production, granulosa cell dysfunction, oocyte telomere shortening and mitochondrial defects, and sperm DNA fragmentation all contribute to reproductive aging. Maneuvers aimed at correcting these abnormalities, including reduction of oxidative stress, improved lifestyle and nutrition, and the role of supplements, are reviewed.
摘要
卵巢睾酮产生减少、颗粒细胞功能障碍、卵母细胞端粒缩短和线粒体缺陷以及精子 DNA 碎片化都导致生殖衰老。本文综述了旨在纠正这些异常的策略，包括降低氧化应激、改善生活方式和营养以及补充剂的作用。
Zotero 插件