Vásquez F, Diaz E, Lera L, Vásquez L, Anziani A, Burrows Raquel
Escuela de Nutrición y Dietética, Facultad de Medicina, Universidad de Chile, Chile.
Nutr Hosp. 2012 Jul-Aug;27(4):1079-85. doi: 10.3305/nh.2012.27.4.5819.
In Chile, the prevalence of obesity in schoolchildren is 21.3%. The study and individual intervention of this malnutrition, it is necessary to have not only global indicators of nutritional status, but also indicators that give information on body composition.
To compare estimates of body fat isotopic dilution, plethysmography and radiographic absorptiometry 4C model in overweight schoolchildren.
We worked with 61 obese (BMI ≥ p 95) of both sexes, between 8 and 13 years, enrolled in a school in a district of the city of Santiago. The multicompartmental body composition determination, considered isotopic dilution, plethysmography and radiographic absorptiometry. Using as a reference standard four compartment model of Fuller.
In both sexes, the method showed better agreement with the reference of 4 compartments was isotope dilution (r = 0.98, p < 0.01). In children, the isotopic dilution underestimates body fat in -0.40 kg. By contrast, DEXA and plethysmography overestimate body fat by 0.81 kg and 1.89 kg respectively. In women, all methods overestimate body fat, with less emphasis isotopic dilution value 0.46 kg, 0.52 kg after DEXA and plethysmography 1.31 kg.
The deuterium isotopic dilution would be the most sensitive method for estimating body fat in research studies because it shows the best agreement with the gold standard multicompartmental model.
在智利,学龄儿童肥胖症的患病率为21.3%。要对这种营养不良情况进行研究和个体干预,不仅需要有营养状况的总体指标,还需要有能提供身体成分信息的指标。
比较超重学龄儿童体内脂肪同位素稀释法、体积描记法和X线吸收测定法4C模型的估算结果。
我们对61名年龄在8至13岁之间、就读于圣地亚哥市某区一所学校的肥胖(BMI≥第95百分位数)男女学生进行了研究。采用同位素稀释法、体积描记法和X线吸收测定法进行多室身体成分测定。以富勒的四室模型作为参考标准。
在男女两性中,与四室参考模型一致性更好的方法是同位素稀释法(r = 0.98,p < 0.01)。在儿童中,同位素稀释法低估体脂0.40千克。相比之下,双能X线吸收法(DEXA)和体积描记法分别高估体脂0.81千克和1.89千克。在女性中,所有方法均高估体脂,同位素稀释法高估0.46千克,DEXA高估0.52千克,体积描记法高估1.31千克。
在研究中,氘同位素稀释法可能是估算体脂最敏感的方法,因为它与金标准多室模型的一致性最佳。