College of Animal Science, South China Agricultural University, Guangzhou, People's Republic of China.
J Virol. 2012 Dec;86(24):13812-3. doi: 10.1128/JVI.02575-12.
Recently, nephropathogenic infectious bronchitis virus (IBV) outbreaks have occurred in commercial broiler flocks and have been associated with a high incidence and morbidity in China. The CK/CH/Zhejiang/06/10 strain (IBV-YX10) was isolated from a 12-day-old broiler chicken in a flock of chickens with swollen speckled kidneys and distended ureters filled with uric acid in China in 2010. Here we reported the complete genomic sequence of the IBV-YX10 which was a natural recombinant nephropathogenic infectious bronchitis virus strain. These findings will contribute additional insights into the molecular characteristics of evolving IBV genomes and the need for effective control of IBV in China.
最近,商业肉鸡群中发生了致病性传染性支气管炎病毒(IBV)暴发,并且与中国的高发病率和高死亡率相关。2010 年,从中国一群肿胀的斑驳肾脏和充满尿酸的扩张输尿管的 12 日龄肉鸡中分离出 CK/CH/Zhejiang/06/10 株(IBV-YX10)。在这里,我们报道了 IBV-YX10 的完整基因组序列,它是一种天然重组的致病性传染性支气管炎病毒株。这些发现将为不断进化的 IBV 基因组的分子特征以及在中国有效控制 IBV 的必要性提供更多的见解。