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年龄、学业成绩与 ADHD 兴奋剂处方:全国队列研究。

Age, academic performance, and stimulant prescribing for ADHD: a nationwide cohort study.

机构信息

Institute for Translational Epidemiology, Mount Sinai School of Medicine, New York, NY 10029, USA.

出版信息

Pediatrics. 2012 Dec;130(6):1012-8. doi: 10.1542/peds.2012-0689. Epub 2012 Nov 19.

Abstract

BACKGROUND

We evaluated whether younger age in class is associated with poorer academic performance and an increased risk of being prescribed stimulants for attention-deficit/hyperactivity disorder (ADHD).

METHODS

This was a nationwide population-based cohort study, linking data from national registries of prescribed drugs and standardized scholastic examinations. The study population comprised all children born in 1994-1996 who took standardized tests in Iceland at ages 9 and 12 (n = 11 785). We estimated risks of receiving low test scores (0-10th percentile) and being prescribed stimulants for ADHD. Comparisons were made according to children's relative age in class.

RESULTS

Mean test scores in mathematics and language arts were lowest among the youngest children in the fourth grade, although the gap attenuated in the seventh grade. Compared with the oldest third, those in the youngest third of class had an increased relative risk of receiving a low test score at age 9 for mathematics (1.9; 95% confidence interval [CI] 1.6-2.2) and language arts (1.8; 95% CI 1.6-2.1), whereas at age 12, the relative risk was 1.6 in both subjects. Children in the youngest third of class were 50% more likely (1.5; 95% CI 1.3-1.8) than those in the oldest third to be prescribed stimulants between ages 7 and 14.

CONCLUSIONS

Relative age among classmates affects children's academic performance into puberty, as well as their risk of being prescribed stimulants for ADHD. This should be taken into account when evaluating children's performance and behavior in school to prevent unnecessary stimulant treatment.

摘要

背景

本研究旨在评估年级较小与较差的学业表现和更高的注意缺陷多动障碍(ADHD)药物治疗风险之间的相关性。

方法

本研究为全国性基于人群的队列研究,将全国处方药物登记处和标准化学校考试的数据进行了关联。研究人群包括所有在 1994 年至 1996 年期间出生并在冰岛分别于 9 岁和 12 岁时接受标准化测试的儿童(n=11785)。我们评估了获得低分(0-10 百分位数)和 ADHD 药物治疗风险的相对风险。比较是根据儿童在班级中的相对年龄进行的。

结果

尽管在七年级时差距有所缩小,但四年级中年龄最小的儿童的数学和语言艺术测试得分最低。与年龄最大的三分之一相比,在班级中年龄最小的三分之一的儿童在 9 岁时获得数学(1.9;95%置信区间[CI]1.6-2.2)和语言艺术(1.8;95%CI1.6-2.1)低分的相对风险增加,而在 12 岁时,这两个科目的相对风险均为 1.6。在 7 至 14 岁之间,年龄最小的三分之一的儿童服用兴奋剂的可能性比年龄最大的三分之一的儿童高 50%(1.5;95%CI1.3-1.8)。

结论

同学中的相对年龄会影响儿童青春期前的学业表现,以及 ADHD 药物治疗的风险。在评估儿童在学校的表现和行为时,应考虑到这一点,以防止不必要的兴奋剂治疗。

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