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ADHD 诊断和兴奋剂处方中实践差异的决定因素:全国监测网络的横断面数据库研究。

Determinants of inter-practice variation in ADHD diagnosis and stimulant prescribing: cross-sectional database study of a national surveillance network.

机构信息

Department of Clinical and Experimental medicine, University of Surrey, Guildford, UK.

Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.

出版信息

BMJ Evid Based Med. 2019 Aug;24(4):155-161. doi: 10.1136/bmjebm-2018-111133. Epub 2019 Feb 14.

Abstract

Early recognition, identification and treatment of children with attention deficit hyperactivity disorder (ADHD) can reduce detrimental outcomes and redirect their developmental trajectory. We aimed to describe variations in age of ADHD diagnosis and stimulant prescribing among general practitioner practices in a nationwide network and identify child, parental, household and general practice factors that might account for these variations. Cross-sectional study of children aged under 19 years registered within a general practice in the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) network in 2016, RCGP RSC has a household key allowing parent and child details to be linked. Data from 158 general practices and 353 774 children under 19 were included. The mean age of first ADHD diagnosis was 10.5 years (95% CI 10.1 to 10.9, median 10, IQR 9.0-11.9) and the mean percentage of children with ADHD prescribed stimulant medications among RCGP RSC practices was 41.2% (95% CI 38.7 to 43.6). There was wide inter-practice variation in the prevalence of diagnosis of ADHD, the age of diagnosis and stimulant prescribing. ADHD diagnosis is more likely to be made later in households with a greater number of children and with a larger age difference between adults and children. Stimulant prescribing for children with ADHD was higher in less deprived practices. Older parents and families with more children fail to recognise ADHD and may need more support. Practices in areas of higher socio-economic status are associated with greater prescribing of stimulants for children with ADHD.

摘要

早期识别、诊断和治疗注意力缺陷多动障碍(ADHD)儿童可以减少不良后果,并改变其发展轨迹。我们旨在描述全国性网络中普通科医生实践中 ADHD 诊断和兴奋剂处方的年龄变化,并确定可能导致这些变化的儿童、父母、家庭和普通科医生因素。2016 年,在皇家全科医师学院(RCGP)研究和监测中心(RSC)网络中的一个普通科医生登记的 19 岁以下儿童的横断面研究,RCGP RSC 有一个家庭密钥,可以将父母和儿童的详细信息链接起来。共纳入了来自 158 个普通科医生和 353774 名 19 岁以下儿童的数据。首次 ADHD 诊断的平均年龄为 10.5 岁(95%CI 10.1-10.9,中位数 10,IQR 9.0-11.9),RCGP RSC 中 ADHD 儿童服用兴奋剂药物的平均比例为 41.2%(95%CI 38.7-43.6)。ADHD 的诊断率、诊断年龄和兴奋剂处方在不同实践中存在广泛差异。家庭中儿童数量越多,成人与儿童之间的年龄差距越大,ADHD 的诊断越有可能推迟。在资源较少的实践中,为 ADHD 儿童开具兴奋剂的情况更为常见。年龄较大的父母和有更多孩子的家庭可能无法识别 ADHD,可能需要更多支持。社会经济地位较高地区的实践与为 ADHD 儿童开具兴奋剂的情况较多有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b5/6678046/998edec63f83/bmjebm-2018-111133f01.jpg

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