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[ICAROS(意大利心脏康复及心脏血运重建术后二级预防调查):心脏康复网络GICR/IACPR首个前瞻性纵向登记的临时报告]

[ICAROS (Italian survey on CardiAc RehabilitatiOn and Secondary prevention after cardiac revascularization): temporary report of the first prospective, longitudinal registry of the cardiac rehabilitation network GICR/IACPR].

作者信息

Griffo Raffaele, Temporelli Pier Luigi, Fattirolli Francesco, Ambrosetti Marco, Tramarin Roberto, Vestri Anna Rita, De Feo Stefania, Tavazzi Luigi

机构信息

U.O. Cardiologia Riabilitativa, ASL 3 Genovese, Ospedale La Colletta, Arenzano, Italy.

出版信息

Monaldi Arch Chest Dis. 2012 Jun;78(2):73-8. doi: 10.4081/monaldi.2012.126.

Abstract

The Italian survey on CardiAc RehabilitatiOn and Secondary prevention after cardiac revascularization (ICAROS) was a multicenter, prospective, longitudinal survey carried out by the Italian Association on Cardiovascular Prevention and Rehabilitation (GICR/IACPR) in patients on completion of a CR program after coronary artery by pass grafting (CABG) and percutaneous coronary intervention (PCI). The aim was to evaluate in the short and medium-term: i) the cardioprotective drug prescription, modification and adherence; ii) the achievement and maintenance of recommended lifestyle targets and risk factor control and their association with cardiovascular events; iii) the predictors of non-adherence to therapy and lifestyle recommendations. The ICAROS results offers a portrait of the "real world" of clinical practice concerning patients after CABG and PCI, and stresses the need to improve secondary prevention care after the index event: many patients after revascularization leave the acute wards without an optimal prescription of preventive medication but the prescription of cardiopreventive drugs and risk factors control is excellent after completion of a CR program. Following CR, the maintenance of evidence-based drugs and lifestyle adherence at one year is fairly good as far as the target goals of secondary prevention are concerned, but to investigate the influence of CR on long-term outcome longer-term studies are required. Last, but not least, ICAROS shows that some characteristics (PCI as index event, living alone, poor eating habits or smoking in young age, and old age, in particular with comorbidities) may identify patients with poor behavioral modification in the medium-term follow-up and in these patients further support may be warranted. In conclusion, participation in CR results in excellent treatment after revascularization, as well as a good lifestyle and medication adherence at 1 year and provides further confirmation of the the benefit of secondary prevention.

摘要

意大利心脏康复与心脏血运重建术后二级预防调查(ICAROS)是一项多中心、前瞻性、纵向调查,由意大利心血管预防与康复协会(GICR/IACPR)针对冠状动脉旁路移植术(CABG)和经皮冠状动脉介入治疗(PCI)后完成心脏康复(CR)计划的患者开展。其目的是在短期和中期评估:i)心脏保护药物的处方、调整及依从性;ii)推荐生活方式目标的达成与维持、危险因素控制及其与心血管事件的关联;iii)不依从治疗和生活方式建议的预测因素。ICAROS的结果描绘了CABG和PCI术后患者临床实践的“真实世界”,并强调在首次事件后改善二级预防护理的必要性:许多血运重建术后的患者离开急性病病房时没有得到预防性药物的最佳处方,但在完成CR计划后,心脏预防药物的处方和危险因素控制情况良好。就二级预防的目标而言,CR后一年基于证据的药物维持和生活方式依从性相当不错,但要研究CR对长期结局的影响,还需要进行长期研究。最后但同样重要的是,ICAROS表明某些特征(以PCI作为首次事件、独居、年轻时饮食习惯差或吸烟以及老年,尤其是伴有合并症)可能在中期随访中识别出行为改变不佳的患者,对这些患者可能需要进一步的支持。总之,参与CR可使血运重建术后获得良好治疗效果,以及一年时良好的生活方式和药物依从性,并进一步证实了二级预防的益处。

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