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风湿性心脏病患儿的三尖瓣修复:长期经验

Triple valve repair in children with rheumatic heart disease: long-term experience.

作者信息

Myers Patrick O, Cikirikcioglu Mustafa, Tissot Cécile, Christenson Jan T, Beghetti Maurice, Kalangos Afksendiyos

机构信息

Division of Cardiovascular Surgery, Geneva University Hospitals, Geneva, Switzerland.

出版信息

J Heart Valve Dis. 2012 Sep;21(5):650-4.

PMID:23167231
Abstract

BACKGROUND AND AIM OF THE STUDY

Triple valve replacement has poor early and long-term results, particularly in children, and few data are available on triple valve repair. Herein are reported the single-center, long-term results of combined aortic, mitral, and tricuspid valve repair in rheumatic children.

METHODS

Ten children (mean age 12 +/- 3 years) with severe rheumatic aortic, mitral, and tricuspid regurgitation underwent triple valve repair over a 17-year period, using a tailored cusp extension to repair the aortic valve, and ring annuloplasty and Carpentier's techniques to repair the mitral and tricuspid valves.

RESULTS

There were no early deaths. During a median follow up of 58 months (range: 3 months to 16 years), no late death occurred and four patients (40%) required reoperation at a median of three years (range: 2.7 to 12 years). Reoperations included one for mitral valve replacement, one for aortic valve replacement, and two for aortic and mitral valve replacements. Freedom from reoperation was 100% at one year, 63 +/- 17% at three, five, and 10 years, and 47 +/- 19% at 15 years.

CONCLUSION

In this particularly challenging patient group, triple valve repair provided satisfactory initial and mid-term results, with a high burden of reoperation in the long term, allowing a median of three years of growth and subsequent placement of a larger valve at the time of actual valve replacement. This strategy might be considered a good palliative surgical approach.

摘要

研究背景与目的

三瓣膜置换术的早期和长期效果不佳,在儿童中尤为如此,且关于三瓣膜修复的数据很少。本文报告了风湿性儿童主动脉瓣、二尖瓣和三尖瓣联合修复的单中心长期结果。

方法

10名患有严重风湿性主动脉瓣、二尖瓣和三尖瓣反流的儿童(平均年龄12±3岁)在17年期间接受了三瓣膜修复,采用定制的瓣叶延长术修复主动脉瓣,采用瓣环成形术和卡彭蒂埃技术修复二尖瓣和三尖瓣。

结果

无早期死亡病例。在中位随访58个月(范围:3个月至16年)期间,无晚期死亡病例,4例患者(40%)在中位3年(范围:2.7至12年)时需要再次手术。再次手术包括1例二尖瓣置换、1例主动脉瓣置换以及2例主动脉瓣和二尖瓣置换。术后1年免于再次手术的比例为100%,3年、5年和10年时为63±17%,15年时为47±19%。

结论

在这个特别具有挑战性的患者群体中,三瓣膜修复提供了令人满意的初期和中期结果,但长期再次手术负担较高,可使患者在中位3年的时间内生长,随后在实际瓣膜置换时植入更大的瓣膜。这种策略可被视为一种良好的姑息性手术方法。

相似文献

1
Triple valve repair in children with rheumatic heart disease: long-term experience.风湿性心脏病患儿的三尖瓣修复:长期经验
J Heart Valve Dis. 2012 Sep;21(5):650-4.
2
Mitral valve repair in children with rheumatic heart disease.风湿性心脏病患儿的二尖瓣修复术。
J Thorac Cardiovasc Surg. 2005 Apr;129(4):875-9. doi: 10.1016/j.jtcvs.2004.11.006.
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Combined mitral and tricuspid valve repair in rheumatic valve disease: fewer reoperations with prosthetic ring annuloplasty.风湿性心脏瓣膜病行二尖瓣和三尖瓣联合修复术:使用瓣环成形环的假体修复可减少再次手术。
Circulation. 2010 May 4;121(17):1934-40. doi: 10.1161/CIRCULATIONAHA.109.894873. Epub 2010 Apr 19.
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Evolution of mitral valve replacement in children: a 40-year experience.儿童二尖瓣置换术的演变:40 年经验。
Ann Thorac Surg. 2012 Feb;93(2):626-33; discussion 633. doi: 10.1016/j.athoracsur.2011.08.085. Epub 2011 Dec 7.
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Very long-term results (more than 20 years) of valve repair with carpentier's techniques in nonrheumatic mitral valve insufficiency.采用Carpentier技术对非风湿性二尖瓣关闭不全进行瓣膜修复的超长期结果(超过20年)
Circulation. 2001 Sep 18;104(12 Suppl 1):I8-11.
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Aortic valve repair for rheumatic aortic valve disease.风湿性主动脉瓣疾病的主动脉瓣修复术。
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Aortic and mitral valve replacement in children: is there any role for biologic and bioprosthetic substitutes?儿童主动脉瓣和二尖瓣置换术:生物及生物人工替代瓣膜有何作用?
Eur J Cardiothorac Surg. 2009 Jul;36(1):84-90; discussion 90. doi: 10.1016/j.ejcts.2009.02.048. Epub 2009 Apr 14.
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Surgery for rheumatic tricuspid valve disease: a 30-year experience.风湿性三尖瓣疾病的外科治疗:30年经验
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Repair of rheumatic tricuspid valve disease: predictors of very long-term mortality and reoperation.风湿性三尖瓣疾病的修复:极长程死亡率和再次手术的预测因素。
Ann Thorac Surg. 2010 Aug;90(2):503-8. doi: 10.1016/j.athoracsur.2010.03.105.

引用本文的文献

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Front Surg. 2015 Nov 10;2:59. doi: 10.3389/fsurg.2015.00059. eCollection 2015.