Aberth W
University of California, Department of Pharmaceutical Chemistry, San Francisco 94143-0446.
Anal Chem. 1990 Mar 15;62(6):609-11. doi: 10.1021/ac00205a013.
A new method for surface-induced dissociation of molecular ions, applied to tandem mass spectrometry, is achieved by collisions at a grazing angle on the inside channel surfaces of a microchannel plate. This technique, termed microchannel SID, is demonstrated by using both positive and negative parent ions in the energy range of 500-2000 eV. Fragmentation spectra of the pentapeptide leucine-enkephalin (555 daltons) at 500 eV show good sequence information with a net fragmentation efficiency of 14%. High mass fragmentation is demonstrated on (CsI)23Cs+ (6113 daltons), with the resultant spectrum showing all cluster fragments from n = 0 to 23.
一种应用于串联质谱的分子离子表面诱导解离新方法，是通过在微通道板内部通道表面以掠角碰撞来实现的。这种技术被称为微通道表面诱导解离（microchannel SID），在500 - 2000 eV能量范围内使用正、负离子母离子进行了演示。500 eV下五肽亮氨酸脑啡肽（555道尔顿）的碎裂谱显示出良好的序列信息，净碎裂效率为14%。在（CsI）₂₃Cs⁺（6113道尔顿）上展示了高质量碎裂，所得谱图显示了从n = 0到23的所有簇碎片。
