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胆固醇脂质性栓塞和类固醇与伊洛前列素联合治疗。

Cholesterol atheroembolism and combined treatment with steroids and iloprost.

机构信息

Servicio de Nefrología. Hospital Universitario 12 de Octubre. Madrid, Spain.

出版信息

Nefrologia. 2012;32(6):824-8. doi: 10.3265/Nefrologia.pre2012.Aug.11645.

Abstract

Cholesterol atheroembolism (CAE) is a systemic disorder whose incidence has increased in recent decades and that presents high morbidity and mortality. Although several therapeutic alternatives have been reported, there is no consensus about the best treatment for this disease. In this paper we report the case of a patient with CAE with skin, bowel and kidney involvement who presented a good response to combined therapy with steroids and prostaglandin analogues. Although there are no conclusive studies, we recommend this therapeutic alternative in the management of CAE with organic failure.

摘要

胆固醇栓子栓塞症(CAE)是一种全身性疾病,其发病率在最近几十年有所增加,且具有较高的发病率和死亡率。尽管已经报道了几种治疗选择,但对于这种疾病的最佳治疗方法尚无共识。在本文中,我们报告了一例伴有皮肤、肠道和肾脏受累的 CAE 患者的病例,该患者对联合使用类固醇和前列腺素类似物治疗反应良好。尽管没有确凿的研究,但我们建议在有机功能衰竭的 CAE 治疗中采用这种治疗选择。

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