与夜间小腿肌肉痉挛相关的因素：病例对照研究。

Factors associated with night-time calf muscle cramps: a case-control study.

机构信息

Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.

出版信息

Muscle Nerve. 2013 Mar;47(3):339-43. doi: 10.1002/mus.23531. Epub 2012 Nov 21.

DOI:10.1002/mus.23531

PMID:23169577

Abstract

INTRODUCTION

Although highly prevalent and painful, night-time calf muscle cramping is poorly understood, and no treatment has shown consistent efficacy or safety.

METHODS

One hundred sixty adults were recruited from New South Wales, Australia, including 80 who had night-time calf cramping at least once per week and 80 age- and gender-matched adults who did not. Participants were assessed using reliable tests of lower limb strength, flexibility, morphometrics, circulation, and sensation, and were questioned about health and lifestyle factors, diet, medications, exercise, symptomatology, sleeping habits, and footwear.

RESULTS

Conditional logistic regression identified 3 factors independently associated with night-time calf muscle cramps: muscle twitching (OR 4.6, 95% CI 1.6-15.5, P = 0.01); lower limb tingling (OR 4.1, 95% CI 1.6-10.3, P = 0.003); and foot dorsiflexion weakness (OR 1.02, 95% CI 1.01-1.03, P = 0.002), which represented other measures of lower limb weakness in the model.

CONCLUSIONS

Night-time calf muscle cramps were associated with markers of neurological dysfunction and potential musculoskeletal therapeutic targets.

摘要

简介

尽管夜间小腿肌肉痉挛非常普遍且疼痛难忍，但目前对此了解甚少，也没有哪种治疗方法显示出一致的疗效和安全性。

方法

在澳大利亚新南威尔士州招募了 160 名成年人，其中 80 名每周至少有一次夜间小腿痉挛，80 名年龄和性别与之匹配但没有夜间小腿痉挛的成年人。参与者接受了可靠的下肢力量、柔韧性、形态学、循环和感觉测试，并被询问了健康和生活方式因素、饮食、药物、运动、症状、睡眠习惯和鞋子等问题。

结果

条件逻辑回归确定了与夜间小腿肌肉痉挛独立相关的 3 个因素：肌肉抽搐（OR 4.6，95%CI 1.6-15.5，P = 0.01）；下肢刺痛（OR 4.1，95%CI 1.6-10.3，P = 0.003）；以及足背屈无力（OR 1.02，95%CI 1.01-1.03，P = 0.002），这在模型中代表了下肢无力的其他测量指标。