General Medicine Department, Faculty of Medicine, University of Strasbourg, Strasbourg, France
General Medicine Department, Faculty of Medicine, University of Strasbourg, Strasbourg, France.
Ann Fam Med. 2018 Jul;16(4):296-301. doi: 10.1370/afm.2238.
Nocturnal leg cramps are a specific kind of cramps affecting almost one-half of patients aged 60 years and older. They reduce patients' quality of sleep and have a negative impact on their quality of life. The aim of this study was to evaluate the association between nocturnal leg cramps and the consumption of alcoholic beverages in patients aged 60 years and older attending general practices.
Case-control study with a Bayesian approach for sensitivity analysis. Participants were voluntary ambulatory patients aged 60 years and older consulting their family doctor. They were recruited in 67 general practices across the Alsace region. Cases (patients having cramps), were matched with controls (patients free from cramps) for age, sex, medical history, and medications known to trigger cramps. Alcohol consumption was assessed through a standardized food frequency questionnaire.
We found an association between the global consumption of alcoholic beverages and nocturnal leg cramps (OR = 6.5, 95% credibility interval, 1.68-38.05; posterior probability 99.82%).
We identified an association between alcohol consumption and nocturnal leg cramps among patients aged 60 years and older attending general practices. These findings have implications for the prevention of cramps.
夜间腿部痉挛是一种特殊的痉挛，影响近一半 60 岁及以上的患者。它们降低了患者的睡眠质量，并对他们的生活质量产生负面影响。本研究旨在评估 60 岁及以上在普通诊所就诊的患者夜间腿部痉挛与饮酒之间的关系。
采用贝叶斯方法进行病例对照研究，以进行敏感性分析。参与者为自愿接受门诊治疗的 60 岁及以上的老年患者。他们在阿尔萨斯地区的 67 家普通诊所招募。病例（有痉挛的患者）与对照组（无痉挛的患者）按年龄、性别、病史和已知引起痉挛的药物相匹配。通过标准化的食物频率问卷评估酒精摄入量。
我们发现，整体饮酒量与夜间腿部痉挛之间存在关联（OR=6.5，95%置信区间，1.68-38.05；后验概率 99.82%）。
我们发现，在普通诊所就诊的 60 岁及以上的患者中，饮酒与夜间腿部痉挛之间存在关联。这些发现对预防痉挛有影响。
