Dabadie A, Roussey M, Treguier C, Defawe G, Babut J M
Service de Pédiatrie et Génétique Médicale, CHU Pontchaillou, RENNES.
Ann Pediatr (Paris). 1990 Jan;37(1):51-3.
We report a case of Sandifer syndrome with chronic torticollis and gastroesophageal reflux (GER). The infant exhibited regurgitations and vomiting from birth. Torticollis with a permanent tilt of the head towards the right developed at age six months. At 16 months, persistence of the vomiting and abnormal attitude of the head and neck led to a CT scan that outruled a brain tumor. Esophageal pH recordings disclosed severe gastroesophageal reflux (pH less than 4 for 46% of the time over 24 hours) and endoscopy showed ulcerated peptic esophagitis. Surgical treatment of the GER ensured both resolution of the reflux and disappearance of the torticollis, establishing the causal relationship between the former and latter manifestations.
我们报告一例伴有慢性斜颈和胃食管反流（GER）的Sandifer综合征病例。该婴儿自出生起就出现反流和呕吐症状。6个月大时出现头部永久性向右倾斜的斜颈。16个月时，呕吐持续存在以及头颈部异常姿势导致进行了CT扫描，排除了脑肿瘤。食管pH监测显示严重的胃食管反流（24小时内46%的时间pH值低于4），内镜检查显示有溃疡性消化性食管炎。对胃食管反流进行手术治疗后，反流症状得到缓解，斜颈也消失了，证实了前一种和后一种表现之间的因果关系。
