Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Acta Psychiatr Scand. 2013 Jul;128(1):34-44. doi: 10.1111/acps.12043. Epub 2012 Nov 22.
The aim of this study was to investigate outcomes of child psychiatric outpatient treatment as usual and to identify outcome predictors, with special regard to attention-deficit/hyperactivity disorder (ADHD), mood disorder, obsessive-compulsive disorder and conduct disorder.
Routinely collected data from 12 613 outpatients between July 2006 and January 2010 in Stockholm, Sweden were analysed. The outcome measure was change in Children's Global Assessment Scale (CGAS) ratings between first visit and case closure (∆CGAS).
CGAS improved during the course of treatment across all diagnostic groups, ranging from a mean change of 4 (mental retardation) to 16 (suicide attempts). ∆CGAS was two times higher in the mood disorder group compared with the ADHD group. In the mood disorder group, several psychotherapies were associated with better outcome but not medication. In the ADHD group, psychotherapeutic interventions were also associated with better outcome, but those who received treatment with central stimulants received less non-medical interventions.
Whereas the functional impairment and the level of improvement in mood disorder corresponded to previous efficacy studies, the ADHD patients were more impaired and improved less after treatment. This should prompt a critical discussion as to whether ADHD patients receive the best available treatment in CAMHS in Stockholm and elsewhere.
本研究旨在调查儿童精神科门诊常规治疗的结果,并确定预后指标,特别关注注意缺陷/多动障碍(ADHD)、心境障碍、强迫症和品行障碍。
对 2006 年 7 月至 2010 年 1 月期间瑞典斯德哥尔摩 12613 名门诊患者的常规数据进行了分析。疗效评价指标为首次就诊和病例结束时儿童总体评估量表(CGAS)评分的变化(∆CGAS)。
所有诊断组在治疗过程中 CGAS 均有所改善,从精神发育迟滞的平均变化 4 分至自杀企图的平均变化 16 分。心境障碍组的 ∆CGAS 比 ADHD 组高两倍。在心境障碍组,几种心理疗法与更好的疗效相关,但药物治疗无关。在 ADHD 组,心理治疗干预也与更好的疗效相关,但接受中枢兴奋剂治疗的患者接受的非药物干预较少。
虽然心境障碍的功能障碍和改善程度与以前的疗效研究一致,但 ADHD 患者在治疗后受损更严重,改善程度较低。这应该引发一场关于 ADHD 患者是否在斯德哥尔摩和其他地方的儿童与青少年心理健康服务机构(CAMHS)中接受最佳可用治疗的批判性讨论。