Biomedical Informatics Center and Center for Genetic Medicine, Northwestern Univesity, Feinberg School of Medicine, 750 North Lake Shore Drive, Chicago, IL 60611, USA.
Nucleic Acids Res. 2013 Jan;41(Database issue):D676-83. doi: 10.1093/nar/gks1064. Epub 2012 Nov 20.
dictyBase (http://dictybase.org) is the model organism database for the social amoeba Dictyostelium discoideum. This contribution provides an update on dictyBase that has been previously presented. During the past 3 years, dictyBase has taken significant strides toward becoming a genome portal for the whole Amoebozoa clade. In its latest release, dictyBase has scaled up to host multiple Dictyostelids, including Dictyostelium purpureum [Sucgang, Kuo, Tian, Salerno, Parikh, Feasley, Dalin, Tu, Huang, Barry et al.(2011) (Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum. Genome Biol., 12, R20)], Dictyostelium fasciculatum and Polysphondylium pallidum [Heidel, Lawal, Felder, Schilde, Helps, Tunggal, Rivero, John, Schleicher, Eichinger et al. (2011) (Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication. Genome Res., 21, 1882-1891)]. The new release includes a new Genome Browser with RNAseq expression, interspecies Basic Local Alignment Search Tool alignments and a unified Basic Local Alignment Search Tool search for cross-species comparisons.
dictyBase（http://dictybase.org）是社会性粘菌 Dictyostelium discoideum 的模式生物数据库。本贡献提供了之前介绍过的 dictyBase 的更新内容。在过去的 3 年中，dictyBase 在成为整个变形菌门的基因组门户方面取得了重大进展。在其最新版本中，dictyBase 已经扩展到可以容纳多个 Dictyostelids，包括 Dictyostelium purpureum [Sucgang、Kuo、Tian、Salerno、Parikh、Feasley、Dalin、Tu、Huang、Barry 等人(2011 年)（比较基因组学的社会变形虫 Dictyostelium discoideum 和 Dictyostelium purpureum。基因组生物学，12，R20)]、Dictyostelium fasciculatum 和 Polysphondylium pallidum [Heidel、Lawal、Felder、Schilde、Helps、Tunggal、Rivero、John、Schleicher、Eichinger 等人(2011 年)（社会变形虫基因组的系统发育分析突出了复杂细胞间通讯的古老起源。基因组研究，21，1882-1891)]。新版本包括一个新的基因组浏览器，具有 RNAseq 表达、种间基本局部对齐搜索工具比对以及跨物种比较的统一基本局部对齐搜索工具搜索。
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