Department of Medical Sciences, Respiratory Medicine & Allergology, Uppsala University, Uppsala, Sweden.
Allergy. 2013 Feb;68(2):213-9. doi: 10.1111/all.12079. Epub 2012 Nov 26.
Asthma and rhinitis have been related to insomnia. The aim of this study was to further analyse the association between asthma, nasal symptoms and insomnia and to identify risk factors for sleep disturbance among patients with asthma, in a large population-based set of material.
In 2008, a postal questionnaire was sent to a random sample of 45 000 adults in four Swedish cities. The questionnaire included questions on insomnia, asthma, rhinitis, weight, height, tobacco use and physical activity.
Twenty-five thousand six hundred and ten subjects participated. Asthma was defined as either current medication for asthma or at least one attack of asthma during the last 12 months, and 1830 subjects (7.15%) were defined as asthmatics. The prevalence of insomnia symptoms was significantly higher among asthmatics than non-asthmatics (47.3% vs 37.2%, <0.0001). In the subgroup reporting both asthma and nasal congestion, 55.8% had insomnia symptoms compared with 35.3% in subjects without both asthma and nasal congestion. The risk of insomnia increased with the severity of asthma, and the adjusted OR for insomnia was 2.65 in asthmatics with three symptoms compared with asthmatics without symptoms. Nasal congestion (OR 1.50), obesity (OR 1.54) and smoking (OR 1.71) also increased the risk of insomnia.
Insomnia remains a common problem among asthmatics. Uncontrolled asthma and nasal congestion are important, treatable risk factors for insomnia. Lifestyle factors, such as smoking and obesity, are also risk factors for insomnia among asthmatics.
哮喘和鼻炎与失眠有关。本研究旨在进一步分析哮喘、鼻部症状与失眠之间的关系,并确定哮喘患者睡眠障碍的危险因素,研究基于大型人群样本。
2008 年,向瑞典四个城市的随机抽取的 45000 名成年人邮寄了一份调查问卷。问卷内容包括失眠、哮喘、鼻炎、体重、身高、吸烟和身体活动情况。
25610 人参与了调查。哮喘的定义为正在使用哮喘药物或在过去 12 个月中至少有一次哮喘发作,1830 名(7.15%)被定义为哮喘患者。哮喘患者的失眠症状发生率明显高于非哮喘患者(47.3% vs 37.2%,<0.0001)。在报告同时患有哮喘和鼻塞的亚组中,55.8%的人有失眠症状,而在没有同时患有哮喘和鼻塞的人群中,这一比例为 35.3%。失眠的风险随着哮喘的严重程度而增加,与无哮喘症状的哮喘患者相比,有三种症状的哮喘患者失眠的调整比值比为 2.65。鼻塞(OR 1.50)、肥胖(OR 1.54)和吸烟(OR 1.71)也增加了失眠的风险。
失眠仍然是哮喘患者的常见问题。未得到控制的哮喘和鼻塞是失眠的重要、可治疗的危险因素。生活方式因素,如吸烟和肥胖,也是哮喘患者失眠的危险因素。