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双侧上颌骨“旋转推进”术治疗阻塞性睡眠呼吸暂停患者:形态变化的三维气道分析。

Bimaxillary 'rotation advancement' procedures in patients with obstructive sleep apnea: a 3-dimensional airway analysis of morphological changes.

机构信息

Department of Craniomaxillofacial and Plastic Surgery, University Cologne, Germany.

出版信息

Int J Oral Maxillofac Surg. 2013 May;42(5):569-78. doi: 10.1016/j.ijom.2012.08.002. Epub 2012 Nov 21.

Abstract

The aim of this retrospective three dimensional (3D) computed tomographic analysis was to investigate the morphological airway changes in 17 obstructive sleep apnea (OSA) patients following bimaxillary rotation advancement procedures. Morphological changes of the nasal cavity and naso-, oro- and hypopharynx were analysed separately, as were the total airway changes using nine parameters of airway size and four of shape. The Wilcoxon test was used to compare airway changes and the intraclass correlation coefficient to qualify inter-observer reliability. Following bimaxillary advancement and anti-clockwise maxillary rotation, the total airway volume and the lateral dimension of the cross-sectional airway increased significantly. The total length of the airway became shorter (p<0.05). Remarkable changes were seen in the oropharynx: the length, volume, cross-sectional area (CSA), antero-posterior and medio-lateral distance changed (p<0.05). This combined with a significant 3D change in the shape of the airway from round to elliptical. The average cross-sectional oropharyngeal area was nearly doubled, the minimal CSA increased 40%, and the hyoid bone was located more anterior and superior. Inter-examiner reliabilities were high (0.89). 3D airway analysis aids the understanding of postoperative pathophysiological changes in OSA patients. The airway became shorter, more voluminous, medio-laterally wider, and more compact and elliptical.

摘要

本回顾性三维(3D)计算机断层扫描分析的目的是研究 17 例阻塞性睡眠呼吸暂停(OSA)患者接受双颌前旋转推进术后气道形态变化。分别分析鼻腔和鼻、口、咽气道的形态变化,以及使用气道大小的九个参数和形状的四个参数分析总气道变化。使用 Wilcoxon 检验比较气道变化,使用组内相关系数(ICC)确定观察者间可靠性。在双颌前伸和上颌逆时针旋转后,总气道容积和气道横截面积的横向尺寸显著增加。气道总长度变短(p<0.05)。口咽气道的长度、体积、横截面积(CSA)、前后径和左右径发生显著变化(p<0.05)。同时气道形状从圆形变为椭圆形,这是一个显著的 3D 变化。气道的平均横截面积增加近一倍,最小 CSA 增加 40%,舌骨更向前和向上移动。观察者间的可靠性很高(0.89)。3D 气道分析有助于理解 OSA 患者术后病理生理变化。气道变短,体积增大,横径变宽,更紧凑和椭圆形。

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