Emeritus professor, Department of Surgery; adjunct clinical professor, Department of Neurosurgery, Medical Center, Stanford University, Stanford, Calif.
Private practice, Beverly Hills, Calif.
Am J Orthod Dentofacial Orthop. 2014 Sep;146(3):385-93. doi: 10.1016/j.ajodo.2014.01.026.
Airway size increases are associated with maxillomandibular advancement (MMA) surgery and improvement or elimination of obstructive sleep apnea (OSA). The 3-dimensional morphologic, volumetric, height, cross-sectional surface area, and diameter changes of the upper airway in patients with OSA after MMA, however, are not well understood.
Patients with moderate or severe OSA who underwent MMA surgery were evaluated by preoperative and postoperative cone-beam computed tomography scans and polysomnograms. The upper airway space was also divided into retropalatal and retroglossal spaces and was analyzed for volumetric, height, cross-sectional surface area, transverse, and anteroposterior diameter changes.
Ten consecutive OSA patients with an average preoperative apnea/hypopnea index of 46 and treated with MMA surgery were included in this study. There were 8 men and 2 women, with an average age of 46 years and an average body mass index of 28. There was an average of a 2.5-fold increase in the total volume of the upper airway space. The retropalatal space increased by 3.5-fold. The retroglossal space increased by 1.5-fold. The greatest change in a cross-sectional area occurred in the transverse axis in both the retroglossal and retropalatal spaces. The average apnea/hypopnea index was 4 postoperatively.
MMA surgery results in a significant increase in the volume and a morphologic airway change from a round to an elliptical f shape in the upper airway space in patients with OSA. The combination of these actions reduces the collapsibility of the upper airway space, hence improving or resolving the OSA.
气道大小的增加与上颌骨前移(MMA)手术以及阻塞性睡眠呼吸暂停(OSA)的改善或消除有关。然而,对于接受 MMA 手术后患有 OSA 的患者,上气道的三维形态、体积、高度、横截面积和直径变化尚不清楚。
对接受 MMA 手术的中重度 OSA 患者进行术前和术后锥形束 CT 扫描和多导睡眠图检查。还对上气道空间进行了划分,分为腭后和舌后空间,并分析了体积、高度、横截面积、横径和前后径的变化。
本研究纳入了 10 例连续接受 MMA 手术治疗的 OSA 患者,平均术前呼吸暂停/低通气指数为 46。这些患者中 8 名男性,2 名女性,平均年龄 46 岁,平均体重指数为 28。上气道空间的总容积平均增加了 2.5 倍。腭后空间增加了 3.5 倍。舌后空间增加了 1.5 倍。横截面积的最大变化发生在舌后和腭后空间的横轴上。术后平均呼吸暂停/低通气指数为 4。
MMA 手术可使 OSA 患者上气道空间的体积显著增加,并使气道形态从圆形变为椭圆形。这些作用的结合降低了上气道空间的塌陷性,从而改善或解决了 OSA。