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棘层松解性毛发管型:头皮寻常型天疱疮的一种皮肤镜表现。

Acantholytic hair casts: a dermoscopic sign of pemphigus vulgaris of the scalp.

作者信息

Pirmez Rodrigo

机构信息

Department of Dermatology, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Brazil.

出版信息

Int J Trichology. 2012 Jul;4(3):172-3. doi: 10.4103/0974-7753.100087.

Abstract

We report the dermoscopic features of pemphigus vulgaris (PV) involving the scalp of a 57-year-old African-American female. Among our findings, there were hair casts - movable tubular structures that envelop the hair shafts. We suggest that the development of those casts occurs through acantholysis within the outer root sheath, a mechanism not yet considered in the literature. This report also highlights how dermoscopy may contribute to the evaluation of disease activity, especially in those cases of PV in which scalp involvement is recalcitrant to treatment. Finally, we recommend that the presence of hair casts should herald the need of therapy adjustment for better disease control.

摘要

我们报告了一名57岁非裔美国女性寻常型天疱疮(PV)累及头皮的皮肤镜特征。在我们的发现中,有毛鞘管——包裹毛干的可移动管状结构。我们认为这些毛鞘管是通过外根鞘内棘层松解形成的,这一机制在文献中尚未被提及。本报告还强调了皮肤镜如何有助于评估疾病活动,特别是在那些头皮受累且治疗效果不佳的PV病例中。最后,我们建议毛鞘管的出现预示着需要调整治疗方案以更好地控制疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a19/3500059/9109c93503ea/IJT-4-172-g001.jpg

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