Center for Primary Health Care Research, Department of Clinical Science, Lund University, Malmö, Sweden.
Acta Paediatr. 2013 Mar;102(3):287-93. doi: 10.1111/apa.12106. Epub 2012 Dec 27.
Preterm birth is associated with a number of physical and mental health issues. The aim of this study was to find out whether there was also any association between individuals born preterm in Sweden between 1984 and 2006 and the risk of unintentional injuries during childhood, adolescence and young adulthood.
The study followed 2 297 134 individuals, including 5.9% born preterm, from 1985 to 2007 for unintentional injuries leading to hospitalization or death (n = 244 021). The males and females were divided into four age groups: 1-5 years, 6-12 years, 13-18 years and 19-23 years. Hazard ratios were calculated for falls, transport injuries and other injuries.
After adjusting for a comprehensive set of covariates, some of the preterm subgroups demonstrated slightly increased risks of unintentional injuries, while others showed slightly decreased risks. However, most of the estimates were borderline or non-significant in both males and females. In addition, the absolute risk differences between individuals born preterm and full term were small.
Despite the association between preterm birth and a variety of physical and mental health consequences, this study shows that there is no consistent risk pattern between preterm birth and unintentional injuries in childhood, adolescence and young adulthood.
早产与许多身心健康问题有关。本研究旨在探讨 1984 年至 2006 年期间在瑞典出生的早产儿与儿童期、青少年期和青年期意外伤害风险之间是否存在关联。
该研究从 1985 年至 2007 年对 2297134 名个体进行了随访,其中包括 5.9%的早产儿,这些个体因意外伤害导致住院或死亡(n=244021)。男性和女性分为四个年龄组:1-5 岁、6-12 岁、13-18 岁和 19-23 岁。计算了跌倒、交通伤害和其他伤害的危害比。
在调整了一整套协变量后,一些早产儿亚组表现出略微增加的意外伤害风险,而其他亚组则表现出略微降低的风险。然而,大多数估计在男性和女性中均处于边缘或无统计学意义。此外,早产儿和足月产儿之间的绝对风险差异较小。
尽管早产与多种身心健康后果有关,但本研究表明,早产与儿童期、青少年期和青年期意外伤害之间没有一致的风险模式。