Mitchell V, Sigala J, Jumeau F, Ballot C, Peers M C, Decanter C, Rives N, Perdrix A, Rigot J-M, Escalier D
EA4308 gamétogenèse et qualité du gamète, 59037 Lille cedex, France.
Gynecol Obstet Fertil. 2012 Dec;40(12):776-9. doi: 10.1016/j.gyobfe.2012.10.003. Epub 2012 Nov 20.
In the management of asthenozoospermia, the spermogram-spermocytogram plays an important role during diagnosis. It is of major importance to distinguish between necrozoospermia and sperm vitality. An ultrastructural study of spermatozoa is processed in the case of primary infertility without female implication, severe, unexplained and irreversible asthenozoospermia, sperm vitality at least 50 % and normal concentration of spermatozoa. Ultrastructural flagellar abnormalities are numerous and involve most spermatozoa. ICSI provides a suitable solution for patients with sperm flagellar defects to conceive children with their own gametes but the rate of ICSI success may be influenced by the type of flagellar abnormality. Some fertilization and birth rate failures which are related to some flagellar abnormalities might occur.
在弱精子症的管理中，精子图谱-精子细胞图谱在诊断过程中起着重要作用。区分死精症和精子活力至关重要。对于原发性不孕（无女方因素）、严重、不明原因且不可逆的弱精子症、精子活力至少50%且精子浓度正常的情况，会对精子进行超微结构研究。超微结构鞭毛异常众多且累及大多数精子。卵胞浆内单精子注射（ICSI）为有精子鞭毛缺陷的患者提供了一种合适的解决方案，使其能够用自身配子受孕，但ICSI的成功率可能会受到鞭毛异常类型的影响。可能会出现一些与某些鞭毛异常相关的受精和出生率失败情况。
