Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Int J Gynaecol Obstet. 2013 Feb;120(2):160-4. doi: 10.1016/j.ijgo.2012.08.024. Epub 2012 Nov 24.
To assess pregnancy outcomes among adolescent girls 16 years old or younger and their newborns.
A cohort study was carried out at Siriraj Hospital, Mahidol University, Bangkok, Thailand, using completed charts for 1061 girls aged 16 years or younger (study group) and 1100 women aged 20 to 29 years (reference group) delivered at that hospital between January 1, 2006, and December 31, 2010. Demographic data, maternal laboratory investigations, maternal complications, placental complications, medications administered in hospital, and neonatal outcomes were recorded.
Anemia (odds ratio [OR], 1.86; confidence interval [CI], 1.52-2.26); heart disease (OR, 0.38; CI 0.15-0.90), thyroid disorder (OR, 0.054; CI, 0.01-0.40), pulmonary disease (OR, 0.89; CI, 0.41-1.93); medical and obstetrics complications including gestational diabetes mellitus (OR, 0.04; CI, 0.01-0.29), placenta previa (OR 1.04, CI 0.06-16.60), preterm labor (OR, 1.98; CI, 1.55-2.53), as well as mean neonatal weight (2830.77 ± 81.31 g and 3038.53 ± 482.23 g; P=0.001) were different in the 2 groups and the differences were statistically significant.
Adverse maternal and neonatal outcomes were common in the study group. Extensive education about contraception and safe sex on the one hand, and an effective care plan if pregnancy occurs, should be provided to teenage girls to reduce these poor outcomes.
评估 16 岁及以下少女及其新生儿的妊娠结局。
本研究为队列研究,在泰国曼谷玛希隆大学 Siriraj 医院进行,使用 2006 年 1 月 1 日至 2010 年 12 月 31 日期间在该院分娩的 1061 名 16 岁及以下少女(研究组)和 1100 名 20 至 29 岁妇女(对照组)的完整病历。记录人口统计学数据、孕产妇实验室检查、孕产妇并发症、胎盘并发症、院内用药和新生儿结局。
贫血(比值比[OR],1.86;95%置信区间[CI],1.52-2.26);心脏病(OR,0.38;95%CI,0.15-0.90),甲状腺疾病(OR,0.054;95%CI,0.01-0.40),肺部疾病(OR,0.89;95%CI,0.41-1.93);包括妊娠期糖尿病(OR,0.04;95%CI,0.01-0.29)、前置胎盘(OR,1.04;95%CI,0.06-16.60)、早产(OR,1.98;95%CI,1.55-2.53)在内的医疗和产科并发症,以及新生儿平均体重(2830.77±81.31 g 和 3038.53±482.23 g;P=0.001)在两组间存在差异,且差异有统计学意义。
研究组中常见不良母婴结局。应向少女提供广泛的避孕和安全性行为教育,以及如果怀孕应提供有效的护理计划,以降低这些不良结局的发生。