McCormack G
New England College of Optometry, Boston, Massachusetts 02115.
Invest Ophthalmol Vis Sci. 1990 Mar 1;31(3):559-68.
Burian proposed that a functional retinotopic remapping of the deviated eye on striate visual cortex may be the physiologic basis for the perceptual phenomenon of anomalous retinal correspondence (ARC) in human strabismus. This investigation searched for this type of retinotopic remapping in five esotropes and one exotrope with ARC by means of visual evoked potential (VEP) topographic mapping. Uniocular stimulation of the foveas (corresponding points) during binocular vision in a normal subject yielded identical VEP scalp topographies from each eye. Stimulation of anomalously corresponding points produced different VEP scalp topographies from each eye in the six strabismic subjects. Uniocular stimulation of the anatomic foveas of each eye (noncorresponding points) in a strabismic subject during binocular vision produced identical VEP scalp topographies. These results suggest that there is no significant functional binocular realignment of retinotopic mapping in the visual cortex of human strabismics with ARC.
布里安提出，斜视眼中偏离的眼睛在纹状视觉皮层上的功能性视网膜拓扑重映射可能是人类斜视中异常视网膜对应（ARC）这种感知现象的生理基础。本研究通过视觉诱发电位（VEP）地形图，在五名内斜视患者和一名有ARC的外斜视患者中寻找这种视网膜拓扑重映射。在正常受试者双眼视觉期间对中央凹（对应点）进行单眼刺激，每只眼睛产生的VEP头皮地形图相同。在六名斜视受试者中，对异常对应点的刺激使每只眼睛产生不同的VEP头皮地形图。在斜视受试者双眼视觉期间，对每只眼睛的解剖学中央凹（非对应点）进行单眼刺激，产生相同的VEP头皮地形图。这些结果表明，患有ARC的人类斜视患者的视觉皮层中，视网膜拓扑映射不存在明显的功能性双眼重新排列。
