• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

鲨鱼直肠腺：氯离子主动转运的模型。

The shark rectal gland: a model for the active transport of chloride.

作者信息

Epstein F H

出版信息

Yale J Biol Med. 1979 Nov-Dec;52(6):517-23.

PMID:231864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2595802/
Abstract

The rectal gland of the spiny dogfish, Squalus acanthias, provides an easily studied model of active chloride transport powered indirectly by Na-K-ATPase. Co-transport of sodium with chloride can be demonstrated in membrane vesicles isolated from basolateral membranes of the gland. Chloride secretion is under the hormonal control of vasoactive intestinal peptide, and possibly other agents, via adenyl cyclase and cyclic AMP. A similar mechanism is probably responsible for the active transport of chloride across other biological membranes.

摘要

棘鲨（Squalus acanthias）的直肠腺提供了一个易于研究的、由钠钾ATP酶间接驱动的主动氯转运模型。钠与氯的协同转运可在从该腺基底外侧膜分离出的膜囊泡中得到证实。氯的分泌受血管活性肠肽以及可能的其他因子通过腺苷酸环化酶和环磷酸腺苷的激素控制。类似的机制可能负责氯在其他生物膜上的主动转运。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5272/2595802/82bdc8774466/yjbm00129-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5272/2595802/82bdc8774466/yjbm00129-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5272/2595802/82bdc8774466/yjbm00129-0027-a.jpg

相似文献

1
The shark rectal gland: a model for the active transport of chloride.鲨鱼直肠腺：氯离子主动转运的模型。
Yale J Biol Med. 1979 Nov-Dec;52(6):517-23.
2
Active chloride transport powered by Na-K-ATPase in shark rectal gland.鲨鱼直肠腺中由钠钾ATP酶驱动的活性氯转运。
Curr Probl Clin Biochem. 1977;8:106-22.
3
Cyclic AMP regulation of active chloride transport in the rectal gland of marine elasmobranchs.环磷酸腺苷对海洋板鳃亚纲动物直肠腺中活性氯转运的调节
J Exp Zool. 1977 Mar;199(3):443-8. doi: 10.1002/jez.1401990319.
4
Hormonal regulation of active chloride transport in the dogfish rectal gland.角鲨直肠腺中活性氯转运的激素调节
Am J Physiol. 1979 Aug;237(2):F138-44. doi: 10.1152/ajprenal.1979.237.2.F138.
5
Transport mechanisms that mediate the secretion of chloride by the rectal gland of Squalus acanthias.介导棘鲛直肠腺分泌氯离子的转运机制。
J Exp Zool. 1997 Dec 1;279(5):504-8.
6
Mechanism of NaCl secretion in the rectal gland of spiny dogfish (Squalus acanthias). I. Experiments in isolated in vitro perfused rectal gland tubules.白斑角鲨（Squalus acanthias）直肠腺中氯化钠分泌的机制。I. 离体灌注直肠腺小管的实验
Pflugers Arch. 1984 Sep;402(1):63-75. doi: 10.1007/BF00584833.
7
Coupled sodium and chloride transport into plasma membrane vesicles prepared from dogfish rectal gland.狗鲨直肠腺制备的质膜囊泡中钠和氯的协同转运。
Pflugers Arch. 1978 Dec 28;378(2):87-92. doi: 10.1007/BF00584439.
8
Mechanism of active chloride secretion by shark rectal gland: role of Na-K-ATPase in chloride transport.鲨鱼直肠腺主动分泌氯离子的机制：钠钾ATP酶在氯离子转运中的作用。
Am J Physiol. 1977 Oct;233(4):F298-306. doi: 10.1152/ajprenal.1977.233.4.F298.
9
Mechanism and control of hyperosmotic NaCl-rich secretion by the rectal gland of Squalus acanthias.棘鲛直肠腺富含氯化钠的高渗分泌的机制与调控
J Exp Biol. 1983 Sep;106:25-41. doi: 10.1242/jeb.106.1.25.
10
Inhibition of chloride secretion by BaCl2 in the rectal gland of the spiny dogfish, Squalus acanthias.氯化钡对白斑角鲨（Squalus acanthias）直肠腺中氯离子分泌的抑制作用。
Life Sci. 1986 Feb 10;38(6):547-52. doi: 10.1016/0024-3205(86)90033-0.

引用本文的文献

1
Multi-tissue RNA-seq and transcriptome characterisation of the spiny dogfish shark (Squalus acanthias) provides a molecular tool for biological research and reveals new genes involved in osmoregulation.多组织RNA测序和白斑角鲨（Squalus acanthias）转录组特征分析为生物学研究提供了一种分子工具，并揭示了参与渗透压调节的新基因。
PLoS One. 2017 Aug 23;12(8):e0182756. doi: 10.1371/journal.pone.0182756. eCollection 2017.
2
Osmotic homeostasis.渗透稳态
Clin J Am Soc Nephrol. 2015 May 7;10(5):852-62. doi: 10.2215/CJN.10741013. Epub 2014 Jul 30.
3
Chloride reabsorption in the rabbit cortical thick ascending limb of the loop of Henle. A sodium dependent process.

本文引用的文献

1
In vitro perfusion of the dogfish rectal gland.姥鲨直肠腺的体外灌注
Am J Physiol. 1974 May;226(5):1188-92. doi: 10.1152/ajplegacy.1974.226.5.1188.
2
Mechanism of active chloride transport: coupled Na/Cl transport by plasma membrane vesicles.活性氯转运机制：质膜囊泡介导的钠/氯协同转运
Trans Assoc Am Physicians. 1978;91:433-43.
3
Sodium-coupled chloride transport by epithelial tissues.上皮组织的钠耦联氯转运
兔髓袢升支粗段皮质部的氯离子重吸收。一种依赖钠的过程。
Pflugers Arch. 1981 Apr;390(1):38-43. doi: 10.1007/BF00582708.
4
Mechanism of NaCl secretion in rectal gland tubules of spiny dogfish (Squalus acanthias). III. Effects of stimulation of secretion by cyclic AMP.白斑角鲨（Squalus acanthias）直肠腺小管中氯化钠分泌的机制。III. 环磷酸腺苷对分泌的刺激作用。
Pflugers Arch. 1984 Dec;402(4):376-84. doi: 10.1007/BF00583938.
5
Vasoactive intestinal polypeptide-induced chloride secretion by a colonic epithelial cell line. Direct participation of a basolaterally localized Na+,K+,Cl- cotransport system.血管活性肠肽诱导结肠上皮细胞系分泌氯离子。基底外侧定位的Na⁺、K⁺、Cl⁻共转运系统的直接参与。
J Clin Invest. 1985 Feb;75(2):462-71. doi: 10.1172/JCI111721.
6
Chloride channels in the luminal membrane of the rectal gland of the dogfish (Squalus acanthias). Properties of the "larger" conductance channel.白斑角鲨（Squalus acanthias）直肠腺腔膜中的氯离子通道。“较大”电导通道的特性。
Pflugers Arch. 1987 Jun;409(1-2):114-21. doi: 10.1007/BF00584757.
Am J Physiol. 1979 Jan;236(1):F1-8. doi: 10.1152/ajprenal.1979.236.1.F1.
4
Cyclic AMP regulation of active chloride transport in the rectal gland of marine elasmobranchs.环磷酸腺苷对海洋板鳃亚纲动物直肠腺中活性氯转运的调节
J Exp Zool. 1977 Mar;199(3):443-8. doi: 10.1002/jez.1401990319.
5
Mechanism of active chloride secretion by shark rectal gland: role of Na-K-ATPase in chloride transport.鲨鱼直肠腺主动分泌氯离子的机制：钠钾ATP酶在氯离子转运中的作用。
Am J Physiol. 1977 Oct;233(4):F298-306. doi: 10.1152/ajprenal.1977.233.4.F298.