角鲨直肠腺中活性氯转运的激素调节
Hormonal regulation of active chloride transport in the dogfish rectal gland.
作者信息
Stoff J S, Rosa R, Hallac R, Silva P, Epstein F H
出版信息
Am J Physiol. 1979 Aug;237(2):F138-44. doi: 10.1152/ajprenal.1979.237.2.F138.
Abstract
Active transport of chloride is modulated by cyclic AMP in the rectal gland of Squalus acanthias. Vasoactive intestinal peptide (VIP) specifically activates the production of cyclic AMP by the gland and stimulates the secretion of chloride. Somatostatin inhibits VIP-induced secretion but has no effect alone. Both these peptides are present in the dogfish shark and may play an important role in electrolyte homeostasis.
摘要
在棘鲛的直肠腺中，氯离子的主动转运受环磷酸腺苷调节。血管活性肠肽（VIP）特异性激活该腺体中环磷酸腺苷的生成，并刺激氯离子分泌。生长抑素抑制VIP诱导的分泌，但单独使用时无作用。这两种肽都存在于角鲨体内，可能在电解质稳态中发挥重要作用。
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