Kumaran Sunitha P, Gupta Kanchan, Pushpa Bt, Viswamitra Sanjaya, Joshy Ev
Department of Radiology, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, Karnataka, India.
J Neurosci Rural Pract. 2012 Sep;3(3):408-10. doi: 10.4103/0976-3147.102645.
We describe a case report where the diagnosis of sporadic Creutzfeldt-Jakob disease(CJD) was suspected by the magnetic resonance imaging (MRI) radiologist in a 75-year-old lady who presented with rapid cognitive decline. MRI revealed cortical T2 and FLAIR(fluid attenuation and inversion recovery) hyperintensities in bilateral fronto-parietal and temporo-occipital locations and showed significant restriction on diffusion-weighted images(DWI). In this case report, we discuss the role of MRI to suspect the diagnosis of CJD in appropriate clinical settings.
我们报告了一例病例,一名75岁女性出现快速认知衰退,磁共振成像(MRI)放射科医生怀疑其患有散发性克雅氏病(CJD)。MRI显示双侧额顶叶和颞枕叶皮质T2加权像及液体衰减反转恢复序列(FLAIR)呈高信号,弥散加权成像(DWI)显示明显受限。在本病例报告中,我们讨论了MRI在适当临床情况下对怀疑CJD诊断的作用。