Krupashankar D S, Manivasagam Shakthi R
Department of Dermatology, Manipal Hospital, Bangalore, India.
Indian Dermatol Online J. 2012 Sep;3(3):177-81. doi: 10.4103/2229-5178.101813.
Psoriasis may be complicated by contact dermatitis due to an impaired cutaneous barrier. Patch testing helps elucidate sensitizers if any.
To determine the prevalence and relevance of secondary contact dermatitis in subjects with psoriasis.
Patch testing with Indian Standard Series was done and readings interpreted after 48 and 96 hours.
Among 110 subjects 47 (42.7%) showed reactions to at least one antigen. Fifteen (13.6%) reacted to fragrance mix, 10 (9.1%) to nickel sulfate, seven (6.4%) to parthenium, and six (5.5%) to balsam of Peru. Palmoplantar psoriasis was the commonest type of psoriasis patch tested. Fragrance mix was the commonest antigen showing 100% current relevance as an aggravating factor of psoriasis. Cosmetics, beauty preparations, skin and healthcare products followed by topical medications were found to be the most common sources of the patch test positivity.
Secondary contact dermatitis is common in patients with psoriasis. Patch testing is necessary to determine the triggering or aggravating antigens in these patients to avoid sensitizers and improve quality of life.
由于皮肤屏障受损，银屑病可能并发接触性皮炎。斑贴试验有助于明确是否存在致敏原。
确定银屑病患者继发接触性皮炎的患病率及相关性。
采用印度标准系列进行斑贴试验，并在48小时和96小时后解读结果。
110名受试者中，47名（42.7%）对至少一种抗原出现反应。15名（13.6%）对香料混合物有反应，10名（9.1%）对硫酸镍有反应，7名（6.4%）对银胶菊有反应，6名（5.5%）对秘鲁香脂有反应。掌跖部银屑病是斑贴试验检测的最常见银屑病类型。香料混合物是最常见的抗原，作为银屑病的加重因素，其当前相关性为100%。化妆品、美容制剂、皮肤和保健产品以及外用药物被发现是斑贴试验阳性的最常见来源。
继发接触性皮炎在银屑病患者中很常见。斑贴试验对于确定这些患者的触发或加重抗原非常必要，以避免致敏原并提高生活质量。
