IEEE J Biomed Health Inform. 2013 May;17(3):654-63. doi: 10.1109/TITB.2012.2228877. Epub 2012 Nov 21.
The Left Ventricular Assist Device (LVAD) is a rotary mechanical pump that is implanted in patients with congestive heart failure to help the left ventricle in pumping blood in the circulatory system. However, using such a device may result in a very dangerous event, called ventricular suction that can cause ventricular collapse due to overpumping of blood from the left ventricle when the rotational speed of the pump is high. Therefore, a reliable technique for detecting ventricular suction is crucial. This paper presents a new suction detection system that can precisely classify pump flow patterns, based on a Lagrangian Support Vector Machine (LSVM) model that combines six suction indices extracted from the pump flow signal to make a decision about whether the pump is in suction, approaching suction, or not in suction. The proposed method has been tested using in vivo experimental data based on two different pumps. The simulation results show that the system can produce superior performance in terms of classification accuracy, stability, learning speed, and good robustness compared to three other existing suction detection methods and the original SVM-based algorithm. The ability of the proposed algorithm to detect suction provides a reliable platform for the development of a feedback control system to control the speed of the pump while at the same time ensuring that suction is avoided.
左心室辅助装置(LVAD)是一种旋转式机械泵,植入充血性心力衰竭患者体内,以帮助左心室在循环系统中泵血。然而,使用这样的设备可能会导致一种非常危险的事件,称为心室抽吸,当泵的转速较高时,由于从左心室过度泵送血液,可能导致心室塌陷。因此,可靠的心室抽吸检测技术至关重要。本文提出了一种新的抽吸检测系统,该系统可以基于拉格朗日支持向量机(LSVM)模型精确分类泵流量模式,该模型结合了从泵流量信号中提取的六个抽吸指数,以决定泵是否处于抽吸状态、接近抽吸状态还是未处于抽吸状态。该方法已使用基于两种不同泵的体内实验数据进行了测试。仿真结果表明,与其他三种现有的抽吸检测方法和基于原始 SVM 的算法相比,该系统在分类准确性、稳定性、学习速度和良好的鲁棒性方面具有优越的性能。该算法检测抽吸的能力为开发反馈控制系统提供了可靠的平台,该系统可以在控制泵的速度的同时,确保避免抽吸。