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VACTERL综合征中的异常腹脐动脉——首例病例报告

Aberrant abdominal umbilical arteries in VACTERL--association: a first case report.

作者信息

Peonim Vichan, Sujirachato Kanchana, Udnoon Jitta, Chudoung Ubon, Wongwichai Sompong

机构信息

Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2012 Oct;95(10):1352-6.

Abstract

A 38-week-gestational age male neonatal death from a 27-year-old-mother was reported. The autopsy found multiple congenital anomalies such as scoliosis of thoracic spine with 13 pairs of ribs, anal atresia, bilateral renal agenesis, and clubfeet. These anomalies were diagnosed VACTERL--association that must include at least three out of six principal anomalies of previously mentioned, e.g., (1) V--vertebral defects, (2) A--anal atresia, (3) C--cardiac anomalies, (4) TE--tracheo-esophageal fistula, (5) R--renal anomalies, and (6) L--limb abnormalities. In addition, other anomalies were also observed in this case, i.e., cryptorchidism both sides, jejunal diverticulum, and aberrant abdominal umbilical arteries.

摘要

据报告,一名27岁母亲所生的孕38周男性新生儿死亡。尸检发现多处先天性异常,如胸椎侧弯伴13对肋骨、肛门闭锁、双侧肾缺如和马蹄内翻足。这些异常被诊断为VACTERL综合征,该综合征必须包括上述六种主要异常中的至少三种,例如:(1)V——脊柱缺损;(2)A——肛门闭锁;(3)C——心脏异常;(4)TE——气管食管瘘;(5)R——肾脏异常;(6)L——肢体异常。此外,该病例还观察到其他异常,即双侧隐睾、空肠憩室和异常的腹脐动脉。

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