Department of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, Tas., Australia.
Acta Paediatr. 2013 Feb;102(2):e90-3. doi: 10.1111/apa.12070. Epub 2012 Nov 30.
Lung lavage using two aliquots of 15 mL/kg of dilute surfactant was performed in 30 ventilated infants with severe meconium aspiration syndrome (MAS). Mean recovery of instilled lavage fluid was 46%, with greater fluid return associated with lower mean airway pressure at 24 h and a shorter duration of respiratory support.
Recovery of instilled lavage fluid is paramount in effective lung lavage in MAS and must be afforded priority in the lavage technique.
对 30 例患有严重胎粪吸入综合征(MAS)的通气婴儿使用两等份 15 毫升/公斤的稀释表面活性剂进行肺灌洗。注入灌洗液的平均回收率为 46%,与较低的平均气道压力和较短的呼吸支持时间相关的更高的液体回收率。
在 MAS 中,有效肺灌洗的关键是灌洗液的回收,因此在灌洗技术中必须优先考虑。