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[结节病肺部的放射性核素研究]

[A radionuclide study of the lungs in sarcoidosis].

作者信息

Obukhov N V, Borisova N K, Daurov B I, Gushchian M E

出版信息

Med Radiol (Mosk). 1990 Mar;35(3):28-33.

PMID:2319920
Abstract

Altogether 43 patients with a primary diagnosis of sarcoidosis of the respiratory organs were investigated to reveal the presence and spreading of dysfunction of external respiratory indices and indices of capillary blood supply in patients with sarcoidosis. Of them sarcoidosis was confirmed clinically in 36. Of the other 7 patients 5 had tuberculosis of various forms, one--lung cancer, and one--chronic obstructive bronchitis. All the patients were subjected to radionuclide investigation with 133Xe, 99mTc-microspheres, and 67Ga-citrate. The results obtained permit objective assessment of the presence and a degree of disorders of external respiration and capillary blood supply and the determination of disease activity on the basis of 67Ga-citrate accumulation that is important for the evaluation of therapeutic efficacy. The results were assessed with relation to a degree of sarcoidosis and the type of a pathological process.

摘要

对43例初步诊断为呼吸器官结节病的患者进行了研究,以揭示结节病患者的肺通气功能指标及毛细血管血液供应指标功能障碍的存在情况及分布。其中36例临床确诊为结节病。另外7例患者中,5例患有各种类型的结核病,1例患有肺癌,1例患有慢性阻塞性支气管炎。所有患者均接受了用133Xe、99mTc - 微球和枸橼酸镓67进行的放射性核素检查。所获结果有助于客观评估肺通气和毛细血管血液供应障碍的存在情况及程度,并根据枸橼酸镓67的蓄积情况确定疾病活动度,这对于评估治疗效果很重要。根据结节病的程度及病理过程类型对结果进行了评估。

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