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2012 年小儿哮喘的研究进展:向哮喘预防迈进。

Advances in pediatric asthma in 2012: moving toward asthma prevention.

机构信息

Division of Pediatric Clinical Pharmacology, Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA.

出版信息

J Allergy Clin Immunol. 2013 Jan;131(1):36-46. doi: 10.1016/j.jaci.2012.11.009. Epub 2012 Nov 27.

Abstract

Last year's "Advances in pediatric asthma: moving forward" concluded the following: "Now is also the time to utilize information recorded in electronic medical records to develop innovative disease management plans that will track asthma over time and enable timely decisions on interventions in order to maintain control that can lead to disease remission and prevention." This year's summary will focus on recent advances in pediatric asthma on modifying disease activity, preventing asthma exacerbations, managing severe asthma, and risk factors for predicting and managing early asthma, as indicated in Journal of Allergy and Clinical Immunology publications in 2012. Recent reports continue to shed light on methods to improve asthma management through steps to assess disease activity, tools to standardize outcome measures in asthma, genetic markers that predict risk for asthma and appropriate treatment, and interventions that alter the early presentation of asthma to prevent progression. We are well on our way to creating a pathway around wellness in asthma care and also to use new tools to predict the risk for asthma and take steps to not only prevent asthma exacerbations but also to prevent the early manifestations of the disease and thus prevent its evolution to severe asthma.

摘要

去年的“儿科哮喘进展:迈向前进”得出以下结论:“现在也是利用电子病历中记录的信息制定创新疾病管理计划的时候了,这些计划将随着时间的推移跟踪哮喘情况,并能够及时做出干预决策,以保持控制,从而导致疾病缓解和预防。”今年的总结将重点关注 2012 年《过敏与临床免疫学杂志》上发表的儿科哮喘在改变疾病活动度、预防哮喘加重、管理严重哮喘以及预测和管理早期哮喘的危险因素方面的最新进展。最近的报告继续阐明通过评估疾病活动度的步骤、哮喘中标准化结果测量的工具、预测哮喘风险和适当治疗的遗传标记以及改变哮喘早期表现以预防进展的干预措施来改善哮喘管理的方法。我们正在努力创建一个围绕哮喘护理健康的途径,同时使用新工具来预测哮喘风险,并采取措施不仅预防哮喘加重,而且预防疾病的早期表现,从而防止其发展为严重哮喘。

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