Andrés Eva, Cordero Alberto, León Montserrat, Alcalde Victor, Laclaustra Martín, Casasnovas José A
Instituto de Investigación 12 de Octubre, Hospital 12 de Octubre, Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, España.
Med Clin (Barc). 2013 Jun 4;140(11):487-92. doi: 10.1016/j.medcli.2012.09.026. Epub 2012 Nov 29.
Hypertension is the most prevalent risk factor in the community. The aim of this study was to describe the risk factors for the progression of blood pressure (BP) from correct values.
Prospective and observational study with 7 years follow-up. BP>140/90 mmHg was considered hypertension. A multivariate model was performed to assess risk factors for BP progression and a predictive score.
The 2,236 males, median age 42 years, had differential characteristics according to their baseline BP category. At the end of the 7-years follow-up 31.9% of baseline-normotensive subjects had an increase of their BP to the range of hypertension. Baseline-normotensive subjects who experienced a progression of BP had higher baseline BP and less favourable lipid profile. A risk score was performed using the following variables: age, hypertension familiar history, overweight and obesity, glucose>100mg/dl, triglycerides>150 mg/dl and uric acid. Total score ranged between -2 and 24; the risk of BP progression beyond normal thresholds increased linearly as the score increased.
Progression of BP from normotension to higher BP categories into the next 7 years in young males and the risk can be estimated by a simple score.
高血压是社区中最普遍的危险因素。本研究的目的是描述血压（BP）从正常水平进展的危险因素。
进行为期7年随访的前瞻性观察研究。血压>140/90 mmHg被视为高血压。采用多变量模型评估血压进展的危险因素及预测评分。
2236名男性，中位年龄42岁，根据其基线血压类别具有不同特征。在7年随访结束时，31.9%的基线血压正常受试者血压升高至高血压范围。经历血压进展的基线血压正常受试者基线血压较高且血脂谱较差。使用以下变量进行风险评分：年龄、高血压家族史、超重和肥胖、血糖>100mg/dl、甘油三酯>150mg/dl和尿酸。总分在-2至24之间；随着评分增加，血压进展超过正常阈值的风险呈线性增加。
年轻男性在未来7年内血压从正常血压进展到更高血压类别的情况以及风险可通过简单评分进行估计。
