Department of Psychology, University of Leuven, Belgium.
J Behav Ther Exp Psychiatry. 2012 Dec;43 Suppl 1:S51-9. doi: 10.1016/j.jbtep.2011.02.001. Epub 2011 Feb 24.
Reduced memory specificity (RMS) is a robust finding in (previously) depressed patients and patients suffering from posttraumatic symptoms. It has been associated with depression severity, rumination, and--more recently--with cue content (e.g., cues referring to highly discrepant self-guides are assumed to hinder specific memory retrieval more likely than cues that match one's self-concept). In this study we have investigated the presence of these relationships in 34 patients diagnosed with borderline personality disorder (BPD). All participants completed the Self-Description Questionnaire (SDQ), the Autobiographical Memory Test (AMT), the Beck Depression Inventory (BDI-II), and the Ruminative Response Scale (RRS). First, it was observed that both rumination and depression severity were associated with RMS. However, when confounding between rumination and depression severity was considered using partial correlations, only depression severity was found to be significantly associated with RMS. Second, in the currently depressed BPD patients (n = 11), memory specificity was significantly related to cue content suggesting that, at least for depressed BPD patients RMS is related to the extent to which cues activate highly discrepant personal domains. Although our data suggest that depression severity as well as current depression (in interaction with cue content) play an important role in the occurrence of RMS in BPD, we will discuss that these findings could be moderated by posttraumatic stress and/or executive functioning.
记忆特异性降低(RMS)是曾患有抑郁症和创伤后症状的患者的一个显著发现。它与抑郁严重程度、反刍思维有关,而且——最近——与线索内容有关(例如,与高度不一致的自我指导相关的线索比与自我概念相符的线索更有可能阻碍特定的记忆检索)。在这项研究中,我们调查了 34 名被诊断为边缘型人格障碍(BPD)的患者中这些关系的存在。所有参与者都完成了自我描述问卷(SDQ)、自传体记忆测试(AMT)、贝克抑郁量表(BDI-II)和反刍反应量表(RRS)。首先,观察到反刍和抑郁严重程度都与 RMS 相关。然而,当使用偏相关考虑反刍和抑郁严重程度之间的混杂时,只有抑郁严重程度与 RMS 显著相关。其次,在目前患有抑郁症的 BPD 患者(n=11)中,记忆特异性与线索内容显著相关,表明至少对于患有抑郁症的 BPD 患者,RMS 与线索激活高度不一致的个人领域的程度有关。尽管我们的数据表明,抑郁严重程度以及当前的抑郁(与线索内容相互作用)在 BPD 中 RMS 的发生中起着重要作用,但我们将讨论这些发现可能会受到创伤后应激和/或执行功能的调节。